ATI RN
Quizlet Pharmacology ATI Questions
Question 1 of 5
Which of the following drugs blocks reuptake of 5-hydroxytryptamine (serotonin)?
Correct Answer: D
Rationale: Serotonin reuptake blockade increases synaptic levels. Buspirone, a 5-HT1A agonist, treats anxiety without reuptake effects. Pizotifen, a serotonin antagonist, prevents migraines. Granisetron, a 5-HT3 antagonist, controls nausea. Paroxetine, an SSRI, potently inhibits serotonin reuptake, elevating mood in depression. Sumatriptan activates 5-HT1 receptors. Paroxetine's mechanism is central to its antidepressant efficacy, distinguishing it from receptor modulators.
Question 2 of 5
While a patient is receiving antilipemic therapy, the nurse knows to monitor the patient closely for the development of which problem?
Correct Answer: D
Rationale: Antilipemic therapy is used to lower cholesterol levels in the blood. This type of therapy often places a strain on the liver as it metabolizes and processes the cholesterol-lowering medications. Therefore, patients receiving antilipemic therapy are at an increased risk of developing liver dysfunction. The nurse should monitor the patient closely for signs and symptoms of liver dysfunction, such as jaundice, abdominal pain, nausea, vomiting, and changes in liver function tests. Early detection and intervention can help prevent serious complications associated with liver dysfunction.
Question 3 of 5
How can central venous access devices (CVADs) be of value in a patient receiving chemotherapy who has stomatitis and severe diarrhea?
Correct Answer: D
Rationale: Central venous access devices (CVADs) can be of value in a patient receiving chemotherapy who has stomatitis and severe diarrhea by allowing concentrated hyperalimentation fluid to be administered through the CVAD. Stomatitis and severe diarrhea can significantly affect oral intake and absorption of nutrients, leading to malnutrition and dehydration. By administering concentrated hyperalimentation fluid through a CVAD, the patient can receive the necessary nutrition and hydration directly into the bloodstream, bypassing the gastrointestinal tract. This can help maintain the patient's nutritional status and manage dehydration effectively during chemotherapy treatment.
Question 4 of 5
The following drugs are absorbed predominantly through active transport systems:
Correct Answer: B
Rationale: Levodopa is absorbed via an active transport mechanism using amino acid transporters, allowing it to cross the blood-brain barrier for its therapeutic effect.
Question 5 of 5
What medication, if ordered for an 8-year-old patient, should the nurse question? (Select all that apply.)
Correct Answer: A
Rationale: Amiodarone, labetalol, and carvedilol are not indicated for pediatric use and do not have established pediatric dosages. Phentolamine and prazosin have established pediatric dosages and would not need to be questioned. The nurse should always verify the appropriateness of medications for pediatric patients, as their pharmacokinetics and pharmacodynamics differ from adults.