ATI RN
ATI Pharmacology Made Easy 4.0 Infection Questions
Question 1 of 5
Which of the following does NOT describe Reye's syndrome :
Correct Answer: D
Rationale: Reye's syndrome is a rare but serious disorder that primarily affects children and teenagers. It is characterized by an acute encephalopathic illness along with fatty degeneration of the liver and other viscera. Reye's syndrome typically arises after a viral infection, such as influenza or chickenpox, rather than being enhanced by sodium and water retention. This condition is not caused by excessive sodium and water retention but rather by a possible link to the use of aspirin during viral infections in children.
Question 2 of 5
A patient receiving a targeted therapy asks the nurse why St. John's wort must be avoided. Which response by the nurse is most appropriate?
Correct Answer: B
Rationale: St. John's wort induces the activity of cytochrome P450 enzymes, which metabolize many targeted therapies. This can lead to decreased blood levels of the targeted therapy, reducing its effectiveness. Patients should be advised to avoid St. John's wort to ensure optimal therapeutic outcomes. The other options are incorrect because St. John's wort does not increase blood levels of targeted therapies, cause overdose, or bind with drugs in the intestinal tract.
Question 3 of 5
The nurse is doing health teaching with a patient with psoriasis. Which nursing implication is a priority for a patient on infliximab to treat psoriasis?
Correct Answer: D
Rationale: Infliximab, a biologic agent used to treat psoriasis, can suppress the immune system and increase the risk of infections and blood disorders. Monitoring the complete blood count (D) is a priority to detect neutropenia, anemia, or thrombocytopenia. Monitoring weight (A), electrolytes (B), or urine output (C) is not typically associated with infliximab therapy.
Question 4 of 5
While caring for a patient with cirrhosis or hepatitis, the nurse knows that abnormalities in which phase of pharmacokinetics may occur?
Correct Answer: C
Rationale: Cirrhosis and hepatitis impair liver function, which directly affects the metabolism of drugs. The liver is responsible for metabolizing many medications through processes such as oxidation, reduction, and hydrolysis. When liver function is compromised, drug metabolism may be slowed, leading to increased drug levels and a higher risk of toxicity. While absorption, distribution, and excretion can also be affected by liver disease, metabolism is the most significantly impacted phase. Therefore, nurses must carefully monitor drug dosages and consider alternative medications for patients with liver dysfunction.
Question 5 of 5
Jonas comes into the local blood donation center. He says he is here to donate platelets only today. The nurse knows this process is called:
Correct Answer: C
Rationale: Apheresis is the process of selectively collecting specific blood components, such as platelets, while returning the remaining components to the donor. This method allows for the efficient collection of platelets without depleting the donor's red blood cells or plasma. Directed donation refers to donating blood for a specific recipient, autologous donation involves donating one's own blood for future use, and allogeneic donation is the standard donation for the general blood supply. Therefore, apheresis is the correct term for platelet-only donation.