Which of the following diuretics inhibits sodium reabsorption in the kidneys while saving K+ and Hydrogen ions?

Correct Answer: A

Rationale: Spironolactone is a potassium-sparing diuretic, which belongs to the aldosterone receptor antagonists. It works by inhibiting aldosterone activity in the distal convoluted tubule and collecting ducts of the kidney. Aldosterone promotes sodium reabsorption in exchange for potassium and hydrogen ions. By blocking aldosterone, Spironolactone allows for increased excretion of sodium while retaining potassium and hydrogen ions, making it a suitable choice for patients who need to maintain potassium levels or are at risk for hypokalemia.

Correct Answer: B

Rationale: Spironolactone is a potassium-sparing diuretic, which means that it helps the body get rid of excess sodium and water while retaining potassium. This is accomplished by blocking the action of aldosterone, a hormone that normally causes the kidneys to retain sodium and water and excrete potassium. Potassium-sparing diuretics like spironolactone are often used in conjunction with other diuretics to prevent potassium loss and maintain electrolyte balance. In contrast, options A, C, and D (Furosemide, Hydrochlorothiazide, Bumetanide) are loop diuretics or thiazide diuretics which promote the excretion of both sodium and potassium.

Correct Answer: C

Rationale: Levothyroxine is a synthetic form of the thyroid hormone thyroxine (T4). It is primarily used for the treatment of hypothyroidism, a condition in which the thyroid gland does not produce enough thyroid hormone. By providing exogenous levothyroxine, the medication helps to restore the normal hormonal balance in the body. This can alleviate symptoms such as fatigue, weight gain, cold intolerance, and other issues related to an underactive thyroid gland. Levothyroxine is not used for the suppression of seizure activity, decreased frequency of migraines, or treatment of ulcers.

Correct Answer: A

Rationale: Warfarin is an anticoagulant medication commonly used to prevent and treat blood clots, specifically thromboembolic events. It works by inhibiting the production of certain clotting factors in the liver, thereby reducing the risk of clot formation in blood vessels. Warfarin is often prescribed for conditions such as atrial fibrillation, deep vein thrombosis, and pulmonary embolism to help prevent strokes, heart attacks, and other complications associated with blood clots. It is not used for suppressing seizure activity, causing laxative action, or relieving anginal attacks.

Correct Answer: C

Rationale: MIMS stands for Monthly Index of Medical Specialties. It is a comprehensive drug database and medical reference resource widely used by healthcare professionals around the world. MIMS provides essential information on prescription and over-the-counter drugs, medical news, disease management guidelines, medical directories, and more. The term "Monthly" in MIMS highlights that the information is regularly updated on a monthly basis to ensure healthcare professionals have access to the most current and reliable information relevant to their practice.