Which of the following diseases is thought to be a

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Lymphatic and Immune System Test Questions Questions

Question 1 of 5

Which of the following diseases is thought to be an autoimmune disease?

A. cancer of the bone marrow B. insulin-dependent diabetes mellitus C. measles and mumps D. duodenal ulcer

Correct Answer: B

Rationale: Insulin-dependent diabetes (Type 1) is autoimmune, attacking pancreatic cells, unlike cancer, viral infections (measles/mumps), or ulcers.

Question 2 of 5

How does the concept of affinity differ from avidity?

A. Affinity refers to the strength of interaction of one binding site whereas avidity is the combined strength of multiple binding sites B. Avidity refers to the strength of interaction of one binding site C. Affinity is the combined strength of multiple binding sites D. Both b and c are correct

Correct Answer: A

Rationale: Affinity is single-site binding strength; avidity is the cumulative strength of multiple sites.

Question 3 of 5

CD8+ T cell activation requires CD4+ T cell help because

A. This acts as a mechanism of regulation to prevent uncontrolled cytotoxicity that could negatively impact healthy cells B. CD4+ T cells sequester the IL-2 produced by CD8+ T cells as a regulatory mechanism C. CD4+ T cells reduce the levels of co-stimulatory activity in the antigen presenting cell which avoids excessive activation of the CD8+ T-cell D. All of the above are correct

Correct Answer: A

Rationale: CD4+ help (via cytokines like IL-2) regulates CD8+ activation, preventing excessive cytotoxicity.

Question 4 of 5

All of the following are true about antibodies, EXCEPT which one?

A. They are glycoproteins B. They are molecules with a single, defined amino acid sequence C. They fix complement D. They occur on the surface of B-lymphocyte

Correct Answer: B

Rationale: Antibodies are glycoproteins , fix complement , and are on B-cells ; they vary in sequence due to diversity.

Question 5 of 5

B cells mature in the_____________.. while T cells mature in the

A. Thymus/bone marrow and gut-associated lymphoid tissue (GALT) B. Spleen/bone marrow and GALT C. Bone marrow and GALT/thymus D. Liver/kidneys

Correct Answer: C

Rationale: B cells mature in bone marrow/GALT, T cells in thymus ; not thymus first or spleen/liver (B, D).

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Which of the following diseases is thought to be an autoimmune disease?

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Lymphatic and Immune System Test Questions Questions

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