ATI RN
Principles of Pharmacology Questions
Question 1 of 5
Which of the following conditions most likely delayed the oral absorption of acetaminophen in the patient?
Correct Answer: C
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 2 of 5
Which of the curves best depicts the log dose-response curve of that agonist when a fixed dose of a competitive α antagonist is given concomitantly?
Correct Answer: B
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 3 of 5
A 17-year-old boy drank increasing amounts of alcohol when attending parties. He noticed that lately he was able to better tolerate alcohol effects and asked his physician the reason for this. The physician said that pharmacodynamic tolerance had probably occurred. Which of the following actions most likely mediated this tolerance?
Correct Answer: B
Rationale: Pharmacodynamic tolerance refers to the body's ability to adapt to the effects of a drug, leading to decreased responsiveness. In this case, the boy's ability to better tolerate alcohol effects indicates a form of tolerance mediated by homeostatic adaptive changes that counteract the drug effect. This type of tolerance involves physiological adjustments to mitigate the impact of the drug, allowing the individual to withstand higher doses. Therefore, the correct answer is B.
Question 4 of 5
A 22-year-old woman suffering from asthma was prescribed albuterol by inhalation. Albuterol is a bronchodilating drug with a molecular weight of 239 daltons. Which of the following permeation processes most likely accounted for the transfer of the drug through the bronchial mucosa?
Correct Answer: B
Rationale: Lipid diffusion is the most likely permeation process for the transfer of albuterol through the bronchial mucosa. Lipid-soluble molecules like albuterol can easily pass through the lipid bilayer of cell membranes. The other options are less likely mechanisms for the absorption of albuterol in this context.
Question 5 of 5
What is the main site of distribution of infliximab, a drug used to treat rheumatoid arthritis?
Correct Answer: A
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.