Which of the following conditions causes profound thrombocytopenia?

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ASCP Hematology Questions Questions

Question 1 of 5

Which of the following conditions causes profound thrombocytopenia?

Correct Answer: A

Rationale: DIC (A) consumes platelets, causing profound thrombocytopenia.

Question 2 of 5

The BEST treatment option for factor VIII hemophiliacs with high titer inhibitor is

Correct Answer: D

Rationale: Recombinant factor VIIa (D) bypasses inhibitors, best for high-titer hemophilia A.

Question 3 of 5

Which of the following tests measures the step from fibrinogen to fibrin conversion?

Correct Answer: D

Rationale: Thrombin time (D) directly assesses fibrinogen to fibrin conversion.

Question 4 of 5

Deficiency of which of the following factors is asymptomatic?

Correct Answer: D

Rationale: Factor XII (E) deficiency doesn’t cause bleeding despite prolonged PTT.

Question 5 of 5

A 6-year- old boy presented three hours after receiving blood transfusion with urticaria, pruritus, maculopapular rash, progressively developed facial edema, and respiratory distress. Of the following, the MOST likely diagnosis is

Correct Answer: C

Rationale: Allergic reaction (C) fits urticaria, edema, and respiratory distress post-transfusion.

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