Which of the following compounds is a good substrate for hypoxanthine-guanine phosphoribosyltransferase in trypanosomes (but not mammals) and is eventually converted into metabolites that are incorporated into RNA?

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NCLEX questions on chemotherapy drugs Questions

Question 1 of 5

Which of the following compounds is a good substrate for hypoxanthine-guanine phosphoribosyltransferase in trypanosomes (but not mammals) and is eventually converted into metabolites that are incorporated into RNA?

Correct Answer: A

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 2 of 5

Plasmodial resistance to chloroquine is due to

Correct Answer: B

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 3 of 5

Which one of the following drugs is recommended as a single agent for oral treatment of uncomplicated malaria due to chloroquine-resistant P falciparum strains?

Correct Answer: C

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 4 of 5

Which one of the following statements about the mechanisms of action of drugs used in cancer chemotherapy is least accurate?

Correct Answer: D

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 5 of 5

All of the following agents have been used in drug regimens for the treatment of breast carcinoma. Which one has specific activity in a subset of female breast cancers?

Correct Answer: D

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

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