Which of the following component molecules is activated in the classical pathway after binding to an Fc?

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NCLEX Pediatric Immunization Questions Questions

Question 1 of 5

Which of the following component molecules is activated in the classical pathway after binding to an Fc?

Correct Answer: A

Rationale: C1 binds to the Fc region of antibodies to initiate the classical pathway.

Question 2 of 5

Which of the following are secreted by macrophages after they have recognized pathogens using pattern recognition molecules (induction phase)?

Correct Answer: D

Rationale: Macrophages secrete TNF (and IL-1/IL-6) during the induction phase.

Question 3 of 5

Which of the following would NOT act initially during mast cell (or basophil) activation?

Correct Answer: D

Rationale: Prostaglandins are secondary mediators produced after initial mast cell degranulation, unlike histamine and proteases which act immediately.

Question 4 of 5

Which of the following is NOT true about live vaccines?

Correct Answer: B

Rationale: Live vaccines are highly effective due to replication and antigen presentation, not the least effective.

Question 5 of 5

Which of the following diseases occurs with the absence of a thymus?

Correct Answer: A

Rationale: DiGeorge's syndrome is characterized by thymic aplasia, impairing T cell development.

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