Which of the following characteristics are similar with respect to Factor VIII and von Willebrand factor (vWF)?

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ATI Hematologic System Quizlet Questions

Question 1 of 5

Which of the following characteristics are similar with respect to Factor VIII and von Willebrand factor (vWF)?

Correct Answer: C

Rationale: Rationale: - Factor VIII and vWF are present in normal to high amounts in newborns due to the physiological immaturity of the hemostatic system. - Choice A is incorrect as vWF is mainly produced in endothelial cells while Factor VIII is produced in both endothelial cells and liver. - Choice B is incorrect as Factor VIII is activated by thrombin, but vWF is not. - Choice D is incorrect as vWF is stored in Weibel-Palade bodies, but Factor VIII is not.

Question 2 of 5

The pathophysiology of venous thrombosis is often explained by Virchow's triad, which includes hypercoagulability, endothelial injury, and venous stasis. Based on Virchow's triad and your knowledge of risk factors for thrombosis, which of the following pediatric patients has the greatest risk of hospital-acquired venous thromboembolism?

Correct Answer: C

Rationale: The correct answer is C because the ex-28 week premature infant requiring NICU-level care for necrotizing enterocolitis has the greatest risk of hospital-acquired venous thromboembolism. Premature infants are at higher risk due to their immature coagulation system and prolonged immobility. Necrotizing enterocolitis further increases the risk due to inflammation and endothelial injury. Hypercoagulability is common in premature infants. Choices A, B, and D have lower risk as they do not have the same combination of risk factors as the premature infant in choice C.

Question 3 of 5

You are treating a patient with localized osteosarcoma of the distal femur with methotrexate, doxorubicin, and cisplatin (MAP) chemotherapy. At week 10 of treatment, the patient undergoes complete resection of the tumor. Pathology demonstrates 40% necrosis. Which of the following represents the most appropriate further therapy?

Correct Answer: D

Rationale: Rationale: The correct answer is D, continuing with MAP chemotherapy. The 40% necrosis rate indicates a good response to the current regimen. Continuing MAP ensures completion of the planned therapy and maximizes the benefit of the initial treatment's response. Choice A (Ifosfamide and etoposide) and B (MAPIE) are not indicated as the response to MAP was favorable. Choice C (Gemcitabine docetaxel) is not the standard of care for osteosarcoma. Continuing with MAP is the most appropriate option for this patient.

Question 4 of 5

A hospitalized client has a platelet count of 58,000/mm3 (58 × 109/L). What action by the nurse is most appropriate?

Correct Answer: D

Rationale: The correct answer is D: Place the client on safety precautions. With a platelet count of 58,000/mm3, the client is at risk for bleeding due to thrombocytopenia. Placing the client on safety precautions will help prevent injuries and minimize bleeding risks. This includes using a soft-bristled toothbrush, avoiding IM injections, and using caution with activities that may cause trauma. A: Encouraging high-protein foods is not directly related to managing the client's thrombocytopenia. B: Neutropenic precautions are for clients with low white blood cell counts, not low platelet counts. C: Limiting visitors to healthy adults is important for clients with compromised immune systems, not specifically for thrombocytopenia.

Question 5 of 5

While taking a client history, which factor(s) that place the client at risk for a hematologic health problem will the nurse document? (Select all that apply.)

Correct Answer: C

Rationale: The correct answer is C: Excessive alcohol consumption. Excessive alcohol intake can lead to hematologic health problems such as anemia and abnormal blood clotting. Alcohol interferes with the production of red blood cells and impairs the function of platelets. Therefore, documenting excessive alcohol consumption is crucial in assessing a client's risk for hematologic issues. Explanation for why other choices are incorrect: A: Family history of military excellence - This choice is irrelevant to hematologic health problems and does not pose a risk factor. B: Diet low in iron and protein - While a poor diet can contribute to hematologic issues, this specific choice does not directly indicate a risk factor for hematologic problems. D: Family history of allergies - Allergies are not directly related to hematologic health problems, so this choice is not relevant in this context.

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