ATI RN
Endocrine Pharmacology Quiz Questions
Question 1 of 5
Which of the following changes in the patient's blood cell concentration most likely occurred as a result of her therapy?
Correct Answer: D
Rationale: The correct answer is D. Therapy typically suppresses the immune system, leading to a decrease in lymphocytes. Lymphocytes are a key component of the immune system, so a decrease is expected with therapy. Neutrophils are primary defenders against infections, so they would not decrease. Erythrocytes are red blood cells responsible for oxygen transport and their decrease would lead to anemia, not a typical therapy response. Basophils are involved in allergic reactions and inflammation, so an increase in basophils would not be a typical response to therapy.
Question 2 of 5
Which of the following drugs would be most appropriate to decrease the patient's symptoms before surgery for uterine fibroids?
Correct Answer: C
Rationale: The correct answer is C: Finasteride. Finasteride is a 5-alpha reductase inhibitor that can decrease the size of uterine fibroids by inhibiting the conversion of testosterone to dihydrotestosterone. This can help reduce symptoms such as heavy menstrual bleeding and pelvic pain before surgery. Ethinyl estradiol (A) is a form of estrogen and can potentially worsen fibroid symptoms. Flutamide (B) is an antiandrogen used for conditions like prostate cancer, not for uterine fibroids. Mifepristone (D) is a progesterone receptor antagonist used for medical abortion, not for managing fibroid symptoms before surgery.
Question 3 of 5
A 26-year-old woman came to her physician complaining of hyperpigmentation of her face. Physical examination revealed a poorly defined, blotchy, masklike zone of facial pigmentation with almost equal involvement of her cheeks, temples, and forehead. Skin biopsy showed increased melanin pigment in basal layers. The woman had been taking a hormonal contraceptive for 6 years. She was a long-distance runner and admitted the use of oxandrolone, erythropoietin, and methamphetamine while training. Which of the following drugs most likely caused the hyperpigmentation in this woman?
Correct Answer: B
Rationale: The correct answer is B: Oxandrolone. Oxandrolone is an anabolic steroid known to cause hyperpigmentation due to increased melanin production. The patient's history of taking oxandrolone aligns with the presentation of hyperpigmentation on her face. Ethinyl estradiol (choice A) is a common component of hormonal contraceptives but is not known to cause hyperpigmentation. Erythropoietin (choice C) is a hormone used to stimulate red blood cell production and is not associated with hyperpigmentation. Norethindrone (choice D) is another hormonal contraceptive component that does not typically cause hyperpigmentation. In this case, the patient's use of oxandrolone is the most likely culprit for her hyperpigmentation.
Question 4 of 5
Which of the following would be the most appropriate pharmacotherapy for a patient with vitamin D deficiency due to inadequate intake?
Correct Answer: A
Rationale: Step 1: Cholecalciferol is the inactive form of vitamin D, which is converted to calcitriol in the body. Step 2: In a patient with vitamin D deficiency due to inadequate intake, supplementing with cholecalciferol is necessary to raise vitamin D levels. Step 3: Calcitriol (choice B) is the active form of vitamin D and is not the first-line treatment for deficiency due to inadequate intake. Step 4: Teriparatide (choice C) is a medication used for osteoporosis, not for treating vitamin D deficiency. Step 5: Cinacalcet (choice D) is used for treating hyperparathyroidism, not for vitamin D deficiency. Summary: Cholecalciferol is the appropriate choice as it directly addresses the deficiency by providing the precursor to active vitamin D, while the other choices are not indicated for this specific situation.
Question 5 of 5
Which of the following drugs should be included in the therapeutic management of this patient?
Correct Answer: C
Rationale: The correct answer is C: Pamidronate. This drug is used in the management of conditions like hypercalcemia, Paget's disease, and osteoporosis, which are commonly associated with cancer patients. It inhibits bone resorption and helps lower calcium levels. Sodium phosphate (A) is a laxative, not indicated for this patient. Hydrochlorothiazide (B) is a diuretic used for hypertension, not for managing the conditions mentioned. Mannitol (D) is an osmotic diuretic mainly used for reducing intracranial pressure, not indicated in this case. Pamidronate is the best choice due to its mechanism of action and relevance to the patient's condition.