ATI RN
Pediatric Immunity NCLEX Questions Questions
Question 1 of 5
Which of the following best describes the role of the pre-B cell receptor (pre BCR)?
Correct Answer: A
Rationale: The pre-BCR signals proliferation and further development of pre-B cells.
Question 2 of 5
Establishment of self-restriction occurs in the thymus and is called ___ selection. Establishment of central self-tolerance occurs in the thymus and is called ___ selection.
Correct Answer: A
Rationale: Positive selection (self-restriction) occurs in the cortex, and negative selection (self-tolerance) occurs in the medulla.
Question 3 of 5
Cellular interactions between B and T cells involve costimulatory activation. There is a physical interaction between ___ on the B cell and ___ on the T cell. This leads to a B cell producing high affinity antibody.
Correct Answer: C
Rationale: CD40 (B cell) and CD154 (T cell) interaction is critical for B-cell activation and antibody affinity maturation.
Question 4 of 5
Expression of L-selectin (CD62L), the receptor that facilitates homing of peripheral lymph nodes, is ___ for memory T cells, ___ for naïve T cells, and ___ for effector T cells.
Correct Answer: B
Rationale: L-selectin is low on memory T cells, high on naïve T cells, and variable on effector T cells.
Question 5 of 5
Mucociliary escalator
Correct Answer: B
Rationale: The mucociliary escalator in the upper respiratory tract clears pathogens.