ATI RN
Pediatric Immunization Practice Questions Questions
Question 1 of 5
Which of the following best describes the location of the delta (δ)-chain locus in human T-cell receptors?
Correct Answer: D
Rationale: The delta (δ)-chain locus is located within the alpha (α)-locus on chromosome 14.
Question 2 of 5
CD4 molecules bind with MHC molecules and are found on (expressed by) cells. CD8 molecules bind with MHC molecules and are found on (expressed by) cells.
Correct Answer: C
Rationale: CD4 binds MHC class II on helper T cells; CD8 binds MHC class I on cytotoxic T cells.
Question 3 of 5
Class II MHC molecules accommodate peptides and thus be referred to analogously as a 'hotdog in a bun', in contrast to class I MHC molecules.
Correct Answer: C
Rationale: Class II MHC binds larger peptides (9-30 residues), resembling a 'hotdog in a bun,' unlike class I.
Question 4 of 5
Rhematoid arthritis
Correct Answer: D
Rationale: Rheumatoid arthritis is associated with HLA-DR4.
Question 5 of 5
In the processing pathway for extracellular antigens, synthesis of MHC class II and invariant chain (li) occurs in the
Correct Answer: C
Rationale: MHC Class II and invariant chain synthesis occurs in the endoplasmic reticulum, where they are assembled before trafficking to vesicles.