Which of the following best describes H1 receptor antagonist:

Correct Answer: D

Rationale: H1 receptor antagonists are primarily used for the treatment and prevention of allergic reactions. They work by blocking the H1 receptors, which are responsible for mediating allergic responses such as itching, swelling, and inflammation. This action helps to alleviate symptoms of allergies like sneezing, itching, and runny nose.

Correct Answer: A

Rationale: The correct way to teach a new staff nurse to obtain a blood sample from a patient with a Portacath is to provide step-by-step instructions and demonstration. Using a Portacath requires specific knowledge and technique to prevent complications such as clot formation or infection. It is important for the preceptor nurse to properly guide and supervise the new staff nurse to ensure patient safety and accurate sample collection.

Correct Answer: B

Rationale: Syrup of ipecac induces vomiting in overdose. It stimulates the chemotactic trigger zone in the medulla-prompting emesis. Gag reflex stimulation is secondary. Suppressing pressures , gag reflex , or motor cortex (E) don't apply. Though less used now, ipecac's CNS action expels pills, aiding this acute scenario, distinct from mechanical or suppressive effects.

Correct Answer: D

Rationale: Hypocalcemia causes muscle spasms (tetany)-nerve hyperexcitability, per classic signs-unlike bruising (coagulation), hypertension (not direct), or wasting (chronic). Spasms dominate, per assessment.

Correct Answer: A

Rationale: Autonomy refers to the patient's right to make informed decisions about their own healthcare. By expressing a desire to avoid life-prolonging measures and requesting a living will, the patient is exercising his autonomy. Beneficence involves acting in the patient's best interest, justice refers to fairness in healthcare, and veracity involves truth-telling. The patient's statements align most closely with the principle of autonomy, as he is asserting his right to control his medical care.

Correct Answer: B

Rationale: When administering packed red blood cells, it is important to use a compatible solution. The preferred solution to administer with packed red blood cells is 0.9% sodium chloride (normal saline) because it is isotonic and compatible with red blood cells. Using an isotonic solution like 0.9% sodium chloride helps to prevent hemolysis of the red blood cells and maintains their integrity during administration. Lactated Ringer's solution, D5W, and 0.45% sodium chloride are not recommended for administering packed red blood cells because they can cause hemolysis due to their hypotonic or hypertonic nature.

Correct Answer: D

Rationale: Glyceryl trinitrate is well-absorbed sublingually due to bypassing the first-pass metabolism, providing rapid relief for angina by dilating blood vessels.

Correct Answer: B

Rationale: Biliary secretion (e.g., rifampin) leads to fecal excretion for some drugs, while others recycle enterohepatically, prolonging action. Not all are fecal-bound-recirculation varies. Gallbladder stores bile, not metabolizes. Many drugs use bile, not rare. Recirculation reflects pharmacokinetics, affecting duration.

Correct Answer: C

Rationale: Levetiracetam treats post-stroke focal seizures by modulating SV2A, offering efficacy, minimal hepatic metabolism, and low interaction risk, ideal for an elderly patient with likely polypharmacy. Phenytoin, a sodium channel blocker, controls seizures but has nonlinear kinetics and P450 induction, risking toxicity. Oxcarbazepine, similar to carbamazepine, has hyponatremia risks, concerning in the elderly. Phenobarbital sedates and interacts via P450. Levetiracetam's safety, renal clearance, and effectiveness in stroke-related epilepsy, per guidelines, make it the most appropriate here.