ATI RN
Pediatric Immune Disorder Test Questions Questions
Question 1 of 5
Which of the following BEST describes cytokines?
Correct Answer: B
Rationale: Cytokines are signaling proteins that recruit and activate immune cells.
Question 2 of 5
Which of the following C1 subunit has the catalytic activity that cleaves C4 and C2 complement proteins?
Correct Answer: C
Rationale: C1s, activated by C1r, cleaves C4 and C2 to form C3 convertase.
Question 3 of 5
Which one of the following is NOT a primary function of phagocytes?
Correct Answer: C
Rationale: Perforins and granzymes are used by cytotoxic T cells and NK cells, not phagocytes like macrophages or neutrophils.
Question 4 of 5
The virus in the above question spreads from the respiratory tract and causes viremia. Which antibody class would be most important in fighting the virus as it spreads through the body?
Correct Answer: D
Rationale: IgG dominates systemic immunity, neutralizing viruses during viremia.
Question 5 of 5
If a person had a genetic defect affecting perforin production, which cells and immune function would be affected?
Correct Answer: A
Rationale: Perforin is critical for cytotoxic T cells and NK cells to kill target cells.