Which of the following benzodiazepines is preferred for elderly patients?

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Cardiovascular Drugs Pharmacology PPT Questions

Question 1 of 5

Which of the following benzodiazepines is preferred for elderly patients?

Correct Answer: D

Rationale: The correct answer is D: Prazepam. Prazepam is preferred for elderly patients due to its long half-life, which reduces the risk of accumulation and potential side effects. Clorazepate (A) and Clordiazepoxide (B) have active metabolites that may accumulate in the elderly. Triazolam (C) has a short half-life, leading to potential next-day sedation. Therefore, Prazepam is the safest choice for elderly patients.

Question 2 of 5

Zafirlucast prevents aspirin-sensitive asthma. This consideration is:

Correct Answer: A

Rationale: Step-by-step rationale: 1. Zafirlukast is a leukotriene receptor antagonist used to treat asthma. 2. Aspirin-sensitive asthma is a condition triggered by aspirin and other NSAIDs. 3. Studies have shown that zafirlukast can prevent bronchoconstriction in aspirin-sensitive asthma. 4. Therefore, the statement that Zafirlukast prevents aspirin-sensitive asthma is TRUE. Summary: - Choice A is correct because zafirlukast has been proven to prevent aspirin-sensitive asthma. - Choice B is incorrect as evidence supports the effectiveness of zafirlukast. - Choice C is incorrect as not all choices are true. - Choice D is incorrect as the correct answer is A, making this choice incorrect.

Question 3 of 5

Which of the following substances is synthesized within vessel walls and inhibits thrombogenesis?

Correct Answer: B

Rationale: The correct answer is B: Prostacyclin (PGI2). Prostacyclin is synthesized within vessel walls and acts as a potent inhibitor of thrombogenesis by inhibiting platelet aggregation and promoting vasodilation. Thromboxane A2 (TXA2) (Choice A) is synthesized by platelets and promotes platelet aggregation. Prostaglandin E (PGE) (Choice C) is involved in various physiological processes but does not specifically inhibit thrombogenesis. Choice D is incorrect as Prostacyclin is indeed synthesized within vessel walls and inhibits thrombogenesis.

Question 4 of 5

This drug is a Class II antiarrhythmic drug:

Correct Answer: B

Rationale: The correct answer is B: Propranolol. Class II antiarrhythmics are beta-blockers, which work by blocking the effects of adrenaline on the heart. Propranolol specifically is a non-selective beta-blocker that reduces heart rate and blood pressure, making it effective in treating certain types of arrhythmias. Flecainide (A) is a Class IC antiarrhythmic, Lidocaine (C) is a Class IB antiarrhythmic, and Verapamil (D) is a Class IV antiarrhythmic. These drugs have different mechanisms of action and are not classified as Class II antiarrhythmics.

Question 5 of 5

Tick the drug with nonselective beta-adrenoblocking activity:

Correct Answer: B

Rationale: The correct answer is B: Propranolol. Propranolol is a nonselective beta-blocker, meaning it blocks both beta-1 and beta-2 adrenergic receptors. This leads to effects such as decreased heart rate, reduced blood pressure, and bronchoconstriction. Atenolol (choice A) and Metoprolol (choice C) are selective beta-1 blockers, primarily affecting the heart. Nebivolol (choice D) is a beta-1 blocker with vasodilatory properties. By blocking both beta-1 and beta-2 receptors, Propranolol has a wider range of effects compared to the other choices.

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