ATI RN
microbiology basic and clinical principles test bank Questions
Question 1 of 9
Which of the following bacteria is responsible for causing the disease known as pneumonia?
Correct Answer: D
Rationale: Rationale: 1. Streptococcus pneumoniae is a common cause of bacterial pneumonia. 2. Mycobacterium tuberculosis can cause a type of pneumonia called tuberculosis. 3. Escherichia coli is not typically associated with pneumonia. 4. "All of the above" includes both Streptococcus pneumoniae and Mycobacterium tuberculosis, which are known to cause pneumonia. Therefore, D is the correct answer.
Question 2 of 9
Which type of bacteria are capable of surviving in high salt concentrations?
Correct Answer: C
Rationale: Correct Answer: C: Halophiles Rationale: 1. Halophiles are bacteria adapted to high salt environments. 2. They have specific mechanisms to tolerate high salt concentrations. 3. Acidophiles thrive in acidic conditions. 4. Thermophiles prefer high temperature environments. 5. Mesophiles grow best at moderate temperatures.
Question 3 of 9
A wound culture grew Gram-negative rods that were oxidase-positive and lactose non-fermenters. What is the most likely microorganism?
Correct Answer: A
Rationale: The correct answer is A: Pseudomonas aeruginosa. P. aeruginosa is a Gram-negative rod that is oxidase-positive and lactose non-fermenting. The positive oxidase test indicates the presence of cytochrome c oxidase, a characteristic of P. aerugin. E. coli is lactose fermenting. Salmonella and Shigella are also Gram-negative rods, but they are lactose fermenters, unlike the lactose non-fermenting P. aeruginosa.
Question 4 of 9
Patients after splenectomy are of high risk of infections caused by:
Correct Answer: D
Rationale: Rationale: After a splenectomy, patients are at high risk of infections caused by encapsulated bacteria such as Streptococcus pneumoniae, Listeria monocytogenes, and Salmonella. The spleen plays a crucial role in the immune response against encapsulated bacteria, and its absence increases susceptibility to these specific pathogens. Therefore, all choices are correct as patients are at risk of infections from all three types of bacteria mentioned.
Question 5 of 9
Which of the following viruses belongs to family Arenaviridae?
Correct Answer: D
Rationale: The correct answer is D: Lassa virus. The rationale is as follows: 1. Lassa virus belongs to the family Arenaviridae, known for causing Lassa fever. 2. Rabies virus belongs to the Rhabdoviridae family. 3. Crimean-Congo hemorrhagic fever virus belongs to the Nairoviridae family. 4. Epstein-Barr virus belongs to the Herpesviridae family. In summary, Lassa virus is the correct answer because it is the only virus listed that belongs to the Arenaviridae family.
Question 6 of 9
The organism that is responsible for the vast majority of cases of fungal vaginitis is:
Correct Answer: D
Rationale: The correct answer is D: Propionibacterium acnes. This bacterium is not a fungus, but a common skin bacteria. Fungal vaginitis is typically caused by Candida albicans or other fungal species, not by bacteria like Escherichia coli, Streptococcus agalactiae, or Klebsiella oxytoca. Propionibacterium acnes is not associated with vaginal infections, making it the correct answer in this context.
Question 7 of 9
What reaction is catalyzed by a beta-lactamase enzyme
Correct Answer: C
Rationale: The correct answer is C: the hydrolysis of the four-membered ring present in penicillin. Beta-lactamase enzyme catalyzes the hydrolysis of the four-membered beta-lactam ring present in penicillin, rendering the antibiotic ineffective against bacterial cell walls. This enzyme breaks the bond in the beta-lactam ring, thus inactivating the antibiotic. Incorrect choices: A: the final cross-linking reaction to form the bacterial cell wall - This is incorrect as beta-lactamase does not participate in the formation of bacterial cell walls. B: the biosynthesis of the penicillin structure from the amino acid valine and cysteine - This is incorrect as beta-lactamase is not involved in the biosynthesis of penicillin. D: the hydrolysis of the acyl side chain from penicillin structures - This is incorrect as beta-lactamase specifically targets the beta-lactam ring, not the
Question 8 of 9
Which of the following bacteria is known for causing the disease tetanus?
Correct Answer: A
Rationale: The correct answer is A: Clostridium tetani. This bacterium is known for causing tetanus due to its ability to produce tetanospasmin, a neurotoxin that leads to the characteristic muscle stiffness and spasms seen in tetanus. Clostridium perfringens (Choice B) is associated with gas gangrene, Streptococcus pyogenes (Choice C) causes streptococcal infections, and Escherichia coli (Choice D) is known for causing various gastrointestinal infections. Therefore, Choices B, C, and D are incorrect as they are not the causative agents of tetanus.
Question 9 of 9
A 30-year-old patient complains about having abdominal pain and diarrhea for five days; body temperature rise up to 37, 5oC along with chills. The day before a patient had been in a forest and drunk from an open water reservoir. Laboratory analyses enabled to make the following diagnosis: amebic dysentery. What is the drug of choice for its treatment?
Correct Answer: A
Rationale: The correct answer is A: Metronidazole. Rationale: 1. Metronidazole is the drug of choice for amebic dysentery due to its effectiveness against the causative agent, Entamoeba histolytica. 2. Metronidazole has good tissue penetration and is able to reach the site of infection in the gut. 3. It is a bactericidal drug that acts by disrupting the DNA structure of the parasite. 4. Metronidazole is well-absorbed orally and has minimal side effects. Summary of other choices: B: Furazolidonum - Not the drug of choice for amebic dysentery. It is primarily used for treating bacterial diarrhea. C: Levomycetin - Not effective against Entamoeba histolytica and not recommended for amebic dysentery. D: Phthalazol - Not commonly used for amebic dysentery treatment. Metronidazole is preferred due