ATI RN
microbiology chapter 12 test bank Questions
Question 1 of 9
Which of the following bacteria is known for producing a neurotoxin that causes paralysis?
Correct Answer: A
Rationale: The correct answer is A: Clostridium botulinum. This bacterium produces the botulinum neurotoxin, which causes paralysis by blocking the release of acetylcholine at neuromuscular junctions. Clostridium perfringens causes gas gangrene, not paralysis. Escherichia coli is associated with gastrointestinal infections, not paralysis. Staphylococcus aureus produces enterotoxins causing food poisoning, not paralysis. Therefore, Clostridium botulinum is the correct choice based on its well-known association with paralysis due to botulinum neurotoxin production.
Question 2 of 9
A family has two children. The younger child is under the year. The child has developed spastic cough attacks. Similar clinical presentation was observed in the elder preschool child one month ago. The doctor suspects pertussis infection. What method enables retrospective diagnostics of this disease?
Correct Answer: A
Rationale: The correct answer is A: Serological. Serological testing involves analyzing blood samples for specific antibodies produced in response to the pertussis infection. This method can detect past infections by identifying the presence of antibodies against the pertussis bacteria in the blood. In this case, since the doctor suspects pertussis infection in both children, serological testing can confirm if they have been exposed to the bacteria. Summary: B: Biological testing does not specifically target pertussis antibodies in the blood. C: Bacteriological testing involves culturing bacteria from samples, which may not be as sensitive for retrospective diagnosis. D: Molecular biological testing focuses on genetic material of the bacteria, which may not provide direct evidence of past infection.
Question 3 of 9
A 33 year old patient was delivered to the infectious diseases department on the 7-th day of disease. He complained about great weakness, high temperature, pain in the lumbar area and leg muscles, icteritiousness, dark color of urine, headache. The acute disease started with chill, body temperature rise up to 40oC, headache, pain in the lumbar area and sural muscles. Icterus turned up on the 4th day, nasal and scleral haemorrhages came on the 5th day. Fever has lasted for 6 days. Diuresis - 200 ml. What is the most probable diagnosis?
Correct Answer: A
Rationale: The most probable diagnosis is Leptospirosis. The symptoms described align with the classic presentation of Leptospirosis, such as fever, muscle pain, headache, jaundice, and hemorrhages. The initial symptoms of chills, high fever, and muscle pain followed by jaundice and hemorrhages are characteristic of Leptospirosis. The presence of dark urine and low diuresis also point towards kidney involvement, which is common in Leptospirosis due to renal failure. Additionally, the patient's history of potential exposure to contaminated water or soil supports the diagnosis, as Leptospirosis is commonly transmitted through contact with infected animal urine. Summary of other choices: - Typhoid fever typically presents with sustained fever, abdominal pain, and constipation, not matching the symptoms described. - Virus A hepatitis usually presents with jaundice, but other symptoms such as muscle pain and hemorrhages are not typical. - Sepsis is a systemic response
Question 4 of 9
A 65-year-old patient with fever and a productive cough had a sputum sample revealing Gram-negative, non-motile, rod-shaped bacteria. What is the most likely causative agent?
Correct Answer: A
Rationale: The correct answer is A: Klebsiella pneumoniae. This bacterium is commonly associated with pneumonia in elderly patients. Klebsiella pneumoniae is a Gram-negative, non-motile, rod-shaped bacterium that frequently causes pneumonia in individuals with underlying health conditions. It is known for its ability to produce a distinctive mucoid capsule. Pseudomonas aeruginosa (B) is more commonly associated with hospital-acquired infections, particularly in immunocompromised individuals. Escherichia coli (C) is a common cause of urinary tract infections but is less likely in this case due to the symptoms and sputum sample results. Haemophilus influenzae (D) is another common respiratory pathogen, but in this scenario, Klebsiella pneumoniae is the most likely causative agent based on the patient's age, symptoms, and the characteristics of the bacteria described in the sputum sample.
Question 5 of 9
When cultured on solid growth media, bacteria with long O-specific chains form:
Correct Answer: A
Rationale: The correct answer is A: Smooth S colonies. Bacteria with long O-specific chains are known as smooth strains, and when cultured on solid growth media, they form smooth colonies due to the presence of the O antigen. This gives them a glossy appearance. Rough R colonies (Choice B) lack O antigen and appear rough. Mucoid -M colonies (Choice C) are associated with capsules, not O-specific chains. H colonies (Choice D) are not relevant to the O-specific chains. Smooth S colonies are the characteristic phenotype of bacteria with long O-specific chains when cultured on solid media.
Question 6 of 9
Examination of duodenal contents revealed some pyriform protozoa with twin nuclei and four pairs of flagella. There were two supporting filaments between the nuclei and a suctorial disc on the ventral side. What representative of protozoa was revealed in this patient?
Correct Answer: D
Rationale: The correct answer is D: Intestinal trichomonad. This protozoan matches the description provided, with pyriform shape, twin nuclei, four pairs of flagella, supporting filaments, and a suctorial disc. Lamblia (A) lacks flagella and supporting filaments. Toxoplasma (B) is an intracellular parasite with different morphology. Leishmania (C) belongs to a different class with no flagella or supporting filaments. In summary, the unique combination of features described in the question points to an intestinal trichomonad, making it the correct answer.
Question 7 of 9
In which phase of mitosis do the chromatids separate?
Correct Answer: C
Rationale: In anaphase, sister chromatids separate and move towards opposite poles of the cell. This is facilitated by the shortening of microtubules attached to the centromeres. Prophase is the phase where chromosomes condense and the nuclear envelope breaks down. Metaphase is when chromosomes align at the metaphase plate. Telophase is when the nuclear envelope reforms and chromosomes decondense. Therefore, anaphase is the correct phase for chromatid separation.
Question 8 of 9
What measures should be applied to prevent hospital-acquired infections:
Correct Answer: D
Rationale: The correct answer is D because all measures mentioned are important in preventing hospital-acquired infections. Isolating the source helps prevent the spread of infections. Isolating at-risk patients reduces their exposure. Increasing patient resistance to infections through proper hygiene and immunizations minimizes susceptibility. Each measure plays a crucial role in infection prevention, making all options correct.
Question 9 of 9
A 10-year-old child had the mantoux tuberculin test administered. 48 hours later a papule up to 8 mm in diameter appeared on the site of the injection. What type of hypersensitivity reaction developed after the tuberculin injection?
Correct Answer: A
Rationale: The correct answer is A: Type IV hypersensitivity reaction. This type of reaction is characterized by a delayed response involving T cells. In this case, the appearance of a papule after 48 hours indicates a delayed hypersensitivity reaction, which is typical of a Type IV reaction. The other choices are incorrect because: B: Arthus phenomenon is a localized immune complex-mediated reaction, not seen in tuberculin tests. C: Seroreaction typically involves antibodies reacting with soluble antigens, not seen in this scenario. D: Type II hypersensitivity reactions involve antibodies targeting specific cells or tissues, which is not the mechanism at play in this case.