Questions 9

ATI RN

ATI RN Test Bank

mastering microbiology test bank Questions

Question 1 of 5

Which of the following bacteria causes the disease diphtheria?

Correct Answer: B

Rationale: The correct answer is B: Corynebacterium diphtheriae. This bacterium produces a toxin that causes diphtheria by inhibiting protein synthesis, leading to the formation of a pseudomembrane in the throat. Bordetella pertussis causes whooping cough, Streptococcus pyogenes causes strep throat, and Neisseria meningitidis causes meningitis. Corynebacterium diphtheriae is the only bacterium among the choices known to cause diphtheria due to its specific toxin production.

Question 2 of 5

Production of auto-antibodies may be due to:

Correct Answer: D

Rationale: Production of auto-antibodies can be due to various factors. Mutant B cell clones can lead to the production of self-reactive antibodies. Antibodies against hidden tissues can also trigger autoimmune responses. Genetic factors play a crucial role in predisposing individuals to autoimmunity. Therefore, the correct answer is D, as all these factors can contribute to the production of auto-antibodies. Choice A is incorrect as it only addresses one possible cause. Choice B is incorrect as it focuses solely on antibodies against hidden tissues. Choice C is incorrect as it overlooks the other potential reasons for auto-antibody production.

Question 3 of 5

Precipitation reaction can be converted into agglutination reaction by coating soluble antigen onto

Correct Answer: D

Rationale: The correct answer is D: All of these. Coating soluble antigen onto Bentonite particles, RBCs, or Latex particles can convert a precipitation reaction into an agglutination reaction. This is because soluble antigens bind to their specific antibodies, causing the particles to clump together, visible as agglutination. Bentonite particles, RBCs, and Latex particles all provide surfaces for the antigen-antibody interaction to occur, leading to agglutination. Therefore, all of these options are correct for converting precipitation reactions to agglutination reactions.

Question 4 of 5

Which of the following is a folate antagonist?

Correct Answer: B

Rationale: The correct answer is B: Trimethoprim. Trimethoprim is a folate antagonist that inhibits dihydrofolate reductase, an enzyme essential for folate metabolism in bacteria. This disrupts bacterial DNA synthesis, leading to bacteriostatic effects. Methyl Penicillin (A) is a beta-lactam antibiotic that interferes with bacterial cell wall synthesis. Vancomycin (C) inhibits cell wall synthesis by binding to D-Ala-D-Ala terminus of cell wall precursors. Gentamicin (D) inhibits bacterial protein synthesis by binding to the 30S subunit of the bacterial ribosome.

Question 5 of 5

What is the primary mode of transmission for tetanus?

Correct Answer: C

Rationale: The correct answer is C: Contaminated wounds. Tetanus is caused by the bacterium Clostridium tetani, which enters the body through breaks in the skin such as wounds or cuts. The bacteria produce a toxin that affects the nervous system, leading to muscle stiffness and spasms. Ingestion of contaminated food (choice A) is not a mode of transmission for tetanus. Inhalation of droplets (choice B) is more relevant for respiratory infections. Direct physical contact (choice D) is not the primary mode of transmission for tetanus as the bacteria need a portal of entry such as a wound to cause infection.

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