ATI RN
microbiology basic and clinical principles test bank Questions
Question 1 of 5
Which of the following bacteria can produce endotoxins that cause septic shock?
Correct Answer: D
Rationale: The correct answer is D because all of the mentioned bacteria (Escherichia coli, Salmonella enterica, and Pseudomonas aeruginosa) are gram-negative bacteria that produce endotoxins in their cell walls. Endotoxins are released when the bacteria are destroyed, leading to the activation of the immune system and potentially causing septic shock. Escherichia coli and Salmonella enterica are common causes of gastrointestinal infections, while Pseudomonas aeruginosa is known for causing infections in immunocompromised individuals. Therefore, all three bacteria can produce endotoxins that contribute to septic shock. Choices A, B, and C are incorrect because each of these bacteria individually can produce endotoxins that lead to septic shock.
Question 2 of 5
What reaction is catalyzed by a beta-lactamase enzyme
Correct Answer: C
Rationale: The correct answer is C: the hydrolysis of the four-membered ring present in penicillin. Beta-lactamase enzyme catalyzes the hydrolysis of the four-membered beta-lactam ring present in penicillin, rendering the antibiotic ineffective against bacterial cell walls. This enzyme breaks the bond in the beta-lactam ring, thus inactivating the antibiotic. Incorrect choices: A: the final cross-linking reaction to form the bacterial cell wall - This is incorrect as beta-lactamase does not participate in the formation of bacterial cell walls. B: the biosynthesis of the penicillin structure from the amino acid valine and cysteine - This is incorrect as beta-lactamase is not involved in the biosynthesis of penicillin. D: the hydrolysis of the acyl side chain from penicillin structures - This is incorrect as beta-lactamase specifically targets the beta-lactam ring, not the
Question 3 of 5
The capsule of Bacillus anthracis is made of
Correct Answer: B
Rationale: The capsule of Bacillus anthracis is made of polypeptide. This is because the capsule is composed of a protein-based material that surrounds the bacterium, providing protection and aiding in its virulence. Polysaccharides, lipids, and the absence of capsules are not characteristic of Bacillus anthracis' capsule structure, making choices A, C, and D incorrect, respectively.
Question 4 of 5
The infectious (non-sterile) immunity is:
Correct Answer: C
Rationale: The correct answer is C because infectious (non-sterile) immunity is achieved through the persistence of the infectious agent in the body, allowing the immune system to continuously recognize and combat the pathogen. This type of immunity provides long-lasting protection against future infections by the same agent. Choice A (cross-reactivity of antibodies) is incorrect as it refers to the ability of antibodies to recognize similar antigens, not necessarily related to infectious immunity. Choice B (toxemia and formation of antitoxic antibodies) is incorrect as it specifically relates to toxins produced by pathogens and the corresponding antibody response, not the persistence of the infectious agent itself. Choice D (neutralization of infectious agent) is incorrect as it describes the process of antibodies binding to and inactivating pathogens, but it does not necessarily lead to long-term immunity through the persistence of the infectious agent.
Question 5 of 5
The most important mechanism of tetracycline resistance is
Correct Answer: C
Rationale: The correct answer is C: Increased active efflux from the bacterial cell. This is the most important mechanism of tetracycline resistance because it involves the bacteria actively pumping out the antibiotic, reducing its intracellular concentration. This prevents tetracycline from effectively targeting bacterial ribosomes. Choice A is incorrect as tetracycline resistance typically involves active efflux rather than reduced influx. Choice B is incorrect because tetracycline resistance mechanisms do not primarily involve altered cell membrane components affecting passive influx. Choice D is also incorrect as tetracycline resistance mechanisms do not typically involve direct enzymatic inactivation of the antibiotic.