Correct Answer: D

Rationale: The correct answer is D because all three bacteria mentioned (Clostridium botulinum, Vibrio cholerae, and Escherichia coli) are capable of producing exotoxins that cause severe diarrhea. Clostridium botulinum produces botulinum toxin leading to botulism, Vibrio cholerae produces cholera toxin causing cholera, and some strains of Escherichia coli produce enterotoxins causing severe diarrhea. Choices A, B, and C alone are incorrect because each of them can produce exotoxins that cause severe diarrhea.

Correct Answer: D

Rationale: The correct answer is D because all three bacteria (Neisseria meningitidis, Haemophilus influenzae, and Streptococcus pneumoniae) can cause bacterial meningitis. Neisseria meningitidis is a common cause of meningococcal meningitis, Haemophilus influenzae can cause H. influenzae meningitis, and Streptococcus pneumoniae is a leading cause of pneumococcal meningitis. Therefore, all of the above choices are correct. The other choices are incorrect because each of the bacteria listed can independently cause bacterial meningitis, so none of them alone can be the sole correct answer.

Correct Answer: B

Rationale: The correct answer is B: BKV. BK virus can cause hemorrhagic cystitis in immunocompromised patients by infecting the urinary tract. It primarily affects the renal tubular epithelial cells, leading to hemorrhagic cystitis. EBV (A) causes infectious mononucleosis, HSV1 (C) causes oral and genital herpes, and JCV (D) causes progressive multifocal leukoencephalopathy, none of which are associated with hemorrhagic cystitis.

Correct Answer: A

Rationale: The correct answer is A: Bordetella pertussis. Bordetella pertussis is the bacterium responsible for causing whooping cough, also known as pertussis. It produces toxins that damage the respiratory tract, leading to severe coughing fits. Haemophilus influenzae, Streptococcus pneumoniae, and Mycobacterium tuberculosis are not associated with whooping cough. Haemophilus influenzae can cause respiratory infections but not whooping cough. Streptococcus pneumoniae is known for causing pneumonia, and Mycobacterium tuberculosis causes tuberculosis, both different from whooping cough. Therefore, the correct answer is A as it is the specific bacterium linked to the disease in question.

Correct Answer: B

Rationale: The correct answer is B: Mycobacterium tuberculosis. Acid-fast bacteria have a unique cell wall component called mycolic acid, making them resistant to decolorization by acid-alcohol during staining. Mycobacterium tuberculosis is acid-fast, as it retains the stain due to its high lipid content. Streptococcus pyogenes (A), Clostridium perfringens (C), and Bacillus subtilis (D) do not possess mycolic acid in their cell walls, so they are not acid-fast.