ATI RN
Drugs Affecting Cardiovascular System Questions
Question 1 of 5
Which of the following autonomic nervous system effects is common for tricyclic antidepressants?
Correct Answer: D
Rationale: The correct answer is D: All of the above. Tricyclic antidepressants like Amitriptyline have all three effects. Antimuscarinic action leads to dry mouth, constipation. Antihistaminic action causes sedation. Alpha adrenoreceptor-blocking action results in orthostatic hypotension. These side effects are common with tricyclic antidepressants due to their pharmacological properties.
Question 2 of 5
Overdoses of cocaine are usually rapidly fatal from:
Correct Answer: D
Rationale: The correct answer is D because overdoses of cocaine can lead to respiratory depression, arrhythmias, and seizures simultaneously, resulting in rapid fatality. Cocaine affects the central nervous system, causing respiratory depression and seizures, while also affecting the heart's electrical activity, leading to arrhythmias. Therefore, all options A, B, and C can occur in combination during a cocaine overdose, contributing to its rapid fatality. The other choices are incorrect because they do not encompass the range of potential fatal outcomes associated with cocaine overdose.
Question 3 of 5
Pick out the bronchodilator drug related to xanthine:
Correct Answer: D
Rationale: The correct answer is D: Theophylline. Theophylline is a bronchodilator drug related to xanthine due to its chemical structure being a xanthine derivative. It works by relaxing the smooth muscles in the airways, thus dilating the bronchioles and improving airflow in conditions like asthma and COPD. A: Atropine is not a xanthine derivative and is mainly used to treat bradycardia and in emergency situations like poisoning. B: Orciprenaline is a beta-2 adrenergic agonist, not a xanthine derivative, used for bronchodilation in conditions like asthma and COPD. C: Adrenaline is a catecholamine and acts as a non-selective adrenergic agonist, primarily used in emergency situations like anaphylaxis and cardiac arrest. It is not a xanthine derivative. In summary, Theophylline is the correct choice
Question 4 of 5
Tick the drug for parenteral iron therapy:
Correct Answer: B
Rationale: The correct answer is B: Fercoven. Parenteral iron therapy involves administering iron intravenously or intramuscularly to treat iron deficiency anemia when oral iron is not effective. Fercoven is a formulation specifically designed for parenteral administration, making it the appropriate choice. Ferrous sulfate, ferrous lactate, and ferrous fumarate are oral iron supplements and are not suitable for parenteral administration. Ferrous sulfate is commonly used orally but can cause gastrointestinal side effects, while ferrous lactate and ferrous fumarate are also oral iron salts. Therefore, Fercoven is the correct choice for parenteral iron therapy.
Question 5 of 5
This drug is useful for treating heart failure because it increases the inotropic state and reduces afterload:
Correct Answer: B
Rationale: The correct answer is B: Amrinone. Amrinone is a phosphodiesterase inhibitor that increases inotropic state by enhancing myocardial contractility and reduces afterload by vasodilation. This dual mechanism helps improve cardiac output in heart failure. A: Amiodarone is an antiarrhythmic drug, not used for inotropic support. C: Propranolol is a beta-blocker that reduces heart rate but does not directly affect inotropic state or afterload. D: Enalapril is an ACE inhibitor that helps reduce afterload but does not have direct inotropic effects.