Which of the following are secreted by macrophages after they have recognized pathogens using pattern recognition molecules (induction phase)?

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NCLEX Pediatric Immunization Questions Questions

Question 1 of 5

Which of the following are secreted by macrophages after they have recognized pathogens using pattern recognition molecules (induction phase)?

Correct Answer: D

Rationale: Macrophages secrete TNF (and IL-1/IL-6) during the induction phase.

Question 2 of 5

Which of the following is NOT true about live vaccines?

Correct Answer: B

Rationale: Live vaccines are highly effective due to replication and antigen presentation, not the least effective.

Question 3 of 5

Which of the following diseases occurs with the absence of a thymus?

Correct Answer: A

Rationale: DiGeorge's syndrome is characterized by thymic aplasia, impairing T cell development.

Question 4 of 5

A 6-year-old presents with the appearance of being intoxicated while walking. Opthlamoscopic findings reveal broken capillaries in the sclera of the eye. Lab work reveals IgA deficiency. Which of the following is the most likely?

Correct Answer: A

Rationale: Ataxia telangiectasia presents with ataxia, telangiectasia (broken capillaries), and often IgA deficiency.

Question 5 of 5

A patient presents at 3-years-old for a follow-up visit. At age 6-months, the patient had a delayed onset of synthesis of an immunoglobulin. At this visit, the mother reports that the recurrent respiratory infections have stopped due to antibiotics and globulin replacement. Which of the following was the most likely for this patient?

Correct Answer: A

Rationale: Transient hypogammaglobulinemia of infancy involves delayed IgG synthesis, resolving with age and supportive care.

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