Which of the following are pluripotential, self-renewing CD34+ cells?

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Pediatric Immunizations NCLEX Questions Questions

Question 1 of 5

Which of the following are pluripotential, self-renewing CD34+ cells?

Correct Answer: A

Rationale: HSCs are pluripotent, self-renewing, and express CD34.

Question 2 of 5

Cortex

Correct Answer: A

Rationale: The cortex contains B cell follicles.

Question 3 of 5

During B cell development, negative selection occurs in an attempt to ensure the antigen receptor:

Correct Answer: D

Rationale: Negative selection eliminates B cells that bind self-antigens to prevent autoimmunity.

Question 4 of 5

What surface immunoglobulins are present once an immature B cell becomes a mature (peripheral) B cell?

Correct Answer: D

Rationale: Mature B cells express both IgM and IgD on their surface.

Question 5 of 5

Where are single-positive (SP) cells found?

Correct Answer: D

Rationale: SP cells mature in the thymus medulla after positive and negative selection.

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