Which of the following are lineage restricted, morphologically identifiable, and express differentiation markers?

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Pediatric Immunization Practice Questions Questions

Question 1 of 5

Which of the following are lineage restricted, morphologically identifiable, and express differentiation markers?

Correct Answer: C

Rationale: Mature cells are fully differentiated, lineage-restricted, and express specific markers.

Question 2 of 5

Paracortex

Correct Answer: B

Rationale: The paracortex is rich in T cells, especially CD4+.

Question 3 of 5

Lymphocyte passage (diapedesis or transmigration) occurs at the between adjacent endothelial cells then into the tissues.

Correct Answer: C

Rationale: Diapedesis occurs at adherens junctions between endothelial cells.

Question 4 of 5

Allelic exclusion creates monospecific B-cell receptors (BCRs). The result is these cells each secrete:

Correct Answer: D

Rationale: Allelic exclusion ensures each B cell produces antibodies with one specificity.

Question 5 of 5

In which of the following developmental stages of T cells are surface molecules CD4 and CD8 NOT expressed?

Correct Answer: A

Rationale: Double-negative (DN) cells lack both CD4 and CD8, unlike DP (both expressed) and SP (one expressed) stages.

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