Which of the following antiseizure drugs is also effective in treating trigeminal neuralgia?

Correct Answer: C

Rationale: Rationale: Carbamazepine is the correct answer because it is a first-line treatment for trigeminal neuralgia due to its mechanism of action in inhibiting voltage-gated sodium channels. This helps reduce neuronal firing and alleviate nerve pain. Primidone and Lamotrigine are not typically used for trigeminal neuralgia. Topiramate may have some efficacy, but it is not as effective as Carbamazepine, which is the drug of choice for treating this condition.

Correct Answer: B

Rationale: Step 1: Buprenorphine is a partial mu receptor agonist with 20-60 times the analgesic potency of morphine. This is due to its high affinity for the mu receptor, resulting in potent analgesic effects. Step 2: Buprenorphine also has a longer duration of action compared to morphine, making it suitable for sustained pain management. Summary: A: Pentazocine is a mixed opioid receptor agonist/antagonist, not a partial mu receptor agonist like buprenorphine. C: Nalbuphine is a kappa receptor agonist and mu receptor antagonist, not a partial mu receptor agonist like buprenorphine. D: Naltrexone is a pure opioid receptor antagonist, not a partial mu receptor agonist like buprenorphine.

Correct Answer: D

Rationale: Step 1: Atypical antipsychotic agents like clozapine have reduced risks of extrapyramidal system dysfunction and tardive dyskinesia compared to typical ones. Step 2: Atypical antipsychotics have low affinity for D1 and D2 dopamine receptors. Step 3: Atypical antipsychotics have high affinity for D4 dopamine receptors. Therefore, the correct answer is D because all the statements are true for atypical antipsychotic agents like clozapine. Other choices are incorrect because they do not cover all the key differences between atypical and typical antipsychotic agents.

Correct Answer: B

Rationale: The correct answer is B: Fluoxetine. Fluoxetine is a Selective Serotonin Reuptake Inhibitor (SSRI) with minimal autonomic toxicity compared to tricyclic antidepressants like Amitriptyline (A), Imipramine (C), and Doxepin (D). SSRIs have a more favorable side effect profile with reduced risk of anticholinergic effects, orthostatic hypotension, and cardiac toxicity. Fluoxetine specifically has a lower affinity for muscarinic, histaminic, and alpha-adrenergic receptors, reducing autonomic side effects. Amitriptyline, Imipramine, and Doxepin are tricyclic antidepressants that have stronger anticholinergic and sedative effects, leading to more autonomic toxicity.

Correct Answer: A

Rationale: Anxiolytics are medications used to treat anxiety disorders, which fall under the category of neurosis. Neurosis is characterized by excessive worry, fear, and distress. Anxiolytics help alleviate symptoms such as restlessness and tension associated with anxiety. Psychosis (choice B) involves loss of touch with reality, narcolepsy (choice C) is a sleep disorder, and bipolar disorders (choice D) involve mood swings between mania and depression. Anxiolytics are not typically indicated for these conditions.