Which of the following antipsychotic drugs has the high risk of potentially fatal agranulocytosis and risk of seizures at high doses?

Correct Answer: C

Rationale: The correct answer is C: Clozapine. Clozapine is known for its high risk of potentially fatal agranulocytosis, a serious blood disorder. It also carries a risk of seizures at high doses. Haloperidol (A) is associated with extrapyramidal symptoms, not agranulocytosis or seizures. Risperidone (B) is less likely to cause agranulocytosis or seizures compared to clozapine. Chlorpromazine (D) can cause agranulocytosis but is not as well-known for this risk as clozapine.

Correct Answer: B

Rationale: Buspirone has a slow onset of action due to its mechanism of action involving serotonin and dopamine receptors. This makes it unsuitable for acute anxiety or panic attacks. The slow onset allows for gradual anxiolytic effects over time. Other choices are incorrect because buspirone has a wide therapeutic index, minimal potential for physical dependence, and does not typically impair mentation or motor functions.

Correct Answer: D

Rationale: The correct answer is D: None of the above. In patients with airway problems, the induction agent of choice is usually propofol. Desflurane (A) and nitrous oxide (B) are not ideal for patients with compromised airways due to their irritant properties and potential for airway reactivity. Halothane (C) is not recommended in patients with airway problems due to its potential for respiratory depression and airway irritation. Therefore, the correct choice is D as propofol is the preferred induction agent in patients with airway issues.

Correct Answer: A

Rationale: The correct answer is A: Misoprostol. Misoprostol is an analog of prostaglandin E1, as it shares similar pharmacological properties. Prostaglandin E1 helps protect the stomach lining and promotes healing of ulcers. Misoprostol, by mimicking prostaglandin E1, can be used to prevent and treat ulcers caused by NSAIDs. De-nol (B) and sucralfate (C) work differently by forming a protective barrier over ulcers. Omeprazole (D) is a proton pump inhibitor that reduces stomach acid production, not an analog of prostaglandin E1.

Correct Answer: A

Rationale: The correct answer is A: Low. Low doses of Aspirin are more effective in inhibiting Thromboxane A2 because they irreversibly inhibit cyclooxygenase-1 in platelets, which is necessary for Thromboxane A2 synthesis. High doses can lead to non-specific inhibition of COX-1 and COX-2, which may cause side effects. Choice B is incorrect because high doses can lead to non-specific inhibition. Choice C is incorrect because high doses are not more effective. Choice D is incorrect as low doses are effective.