ATI RN
ABVD chemotherapy drugs Questions
Question 1 of 5
Which of the following antimalarial drugs causes a dose-dependent toxic state that includes flushed and sweaty skin, dizziness, nausea, diarrhea, tinnitus, blurred vision, and impaired hearing?
Correct Answer: D
Rationale: Quinine causes cinchonism, a dose-dependent toxicity with symptoms like tinnitus, blurred vision, and nausea.
Question 2 of 5
In a patient with diffuse lymphoma, the oncologist suggests a treatment strategy that involves the initial administration of doxorubicin to obtain a significant logkill, followed by the cell cycle-specific drugs cytarabine and vincristine. This therapeutic strategy is called
Correct Answer: B
Rationale: Recruitment involves using a non-cycle-specific drug (doxorubicin) to kill a large number of cells, followed by cycle-specific drugs (cytarabine, vincristine) to target remaining cycling cells.
Question 3 of 5
Which one of the following is least likely to be a mechanism of cancer cell resistance to antineoplastic drugs?
Correct Answer: B
Rationale: Decreased activity of activating enzymes is less common as a resistance mechanism compared to the others listed, which are well-documented.
Question 4 of 5
Cyclosporine is effective in organ transplantation. The immunosuppressant action of the drug appears to be due to
Correct Answer: D
Rationale: Cyclosporine inhibits interleukin gene transcription (e.g., IL-2) by blocking calcineurin, suppressing T-cell activation in transplantation.
Question 5 of 5
Which one of the following agents acts at the step of antigen recognition?
Correct Answer: D
Rationale: Rh0 (D) immune globulin prevents antigen recognition by coating Rh-positive fetal RBCs, blocking maternal immune response.