Which of the following Antibodies occurs as a pentameric structure?

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Pediatric Immune Disorder Test Questions Questions

Question 1 of 5

Which of the following Antibodies occurs as a pentameric structure?

Correct Answer: A

Rationale: IgM is the only antibody that naturally occurs as a pentamer, consisting of five monomeric units linked by a J chain, enhancing its ability to bind multiple antigens simultaneously.

Question 2 of 5

A medical student wants to perform a study on MACROPHAGES type 1, the best way to get these cells is by

Correct Answer: C

Rationale: M1 macrophages are pro-inflammatory and induced by IFN-γ and LPS stimulation of monocytes, not IL-10 (which promotes M2). Answer provided as C based on immunology.

Question 3 of 5

which of the following cells is not from a myeloid origin

Correct Answer: C

Rationale: NK cells are lymphoid, not myeloid; others (macrophages, neutrophils, mast cells) are myeloid-derived.

Question 4 of 5

Which of the following BEST describes cytokines?

Correct Answer: B

Rationale: Cytokines are signaling proteins that recruit and activate immune cells.

Question 5 of 5

Depressed levels of MHC class I molecules on virus infected host cells can be detected by

Correct Answer: D

Rationale: NK cells detect and kill cells with reduced MHC class I, a viral evasion strategy.

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