ATI RN
ATI Hematologic System Test Questions
Question 1 of 5
Which of the following alters the function of thrombin from a procoagulant protein to one that downregulates the formation of fibrinogen?
Correct Answer: D
Rationale: Thrombomodulin alters thrombin's function by binding to it and activating protein C. Activated protein C then inhibits factors Va and VIIIa, which are essential for the formation of fibrinogen. Protein C (choice A) also inhibits coagulation, but it doesn't directly alter thrombin's function. Protein S (choice B) enhances protein C's activity but doesn't directly affect thrombin. Antithrombin (choice C) inhibits thrombin and other coagulation factors, but it doesn't specifically alter thrombin's function to downregulate fibrinogen formation.
Question 2 of 5
Which of the following best characterizes the function of ferroportin in iron metabolism?
Correct Answer: D
Rationale: Ferroportin is a transmembrane iron exporter responsible for releasing iron from cells into the bloodstream. It is crucial in regulating systemic iron levels. Choice A is incorrect as storage iron is typically stored as ferritin. Choice B is incorrect as ferroportin is not found in the plasma but on cell membranes. Choice C is incorrect as erythroid progenitors do not directly interact with ferroportin. Therefore, the correct answer is D as it accurately describes the function of ferroportin in iron metabolism.
Question 3 of 5
You are discussing prognosis with the mother of a patient with stage 3, group III rhabdomyosarcoma. Which of the following is the most unfavorable primary site?
Correct Answer: A
Rationale: The correct answer is A: Extremity. Rhabdomyosarcoma has a better prognosis when located in the extremities compared to other sites due to easier surgical resection and less risk of metastasis. Prostate (B) is less common in children and has a poorer prognosis. Infratemporal fossa (C) and neck (D) sites have a higher risk of local invasion and metastasis, leading to a worse prognosis compared to extremity sites.
Question 4 of 5
A client is having a bone marrow aspiration and biopsy. What action by the nurse takes priority?
Correct Answer: B
Rationale: The correct answer is B: Ensure that valid consent is in the medical record. This is the priority because obtaining informed consent is essential before any invasive procedure like a bone marrow aspiration and biopsy. It ensures that the client understands the procedure, risks, benefits, and alternatives. Administering pain medication (A), having the client shower (C), and premedicating with sedatives (D) are important aspects of care but obtaining valid consent is crucial for legal and ethical reasons before proceeding with the procedure.
Question 5 of 5
An older client asks the nurse why 'people my age' have weaker immune systems than younger people. What responses by the nurse are best? (Select all that apply.)
Correct Answer: C
Rationale: Rationale: - As we age, there is a decrease in the production of plasma proteins, which are essential for immune function. - Lower levels of plasma proteins can lead to a weaker immune response. - This decline in plasma proteins can make older individuals more susceptible to infections. - Choices A, B, and D are incorrect as they do not directly address the impact of aging on immune system function.