ATI RN
Cardiovascular System Drugs Classification Questions
Question 1 of 5
Which of the following agents is a beta2–selective antagonist?
Correct Answer: D
Rationale: The correct answer is D: Butoxamine. Butoxamine is a beta2-selective antagonist due to its high affinity for beta2-adreagent receptors over beta1 receptors. This selectivity allows it to block the effects of beta2 activation specifically. Tolazoline (A) is an alpha-adrenergic antagonist, Pindolol (B) is a non-selective beta-blocker, and Ergotamine (C) is a serotonin receptor agonist. Therefore, they are not beta2-selective antagonists.
Question 2 of 5
The antiseizure drug, which induces hepatic microsomal enzymes, is:
Correct Answer: B
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 3 of 5
Which of the following statements is correct for levodopa?
Correct Answer: D
Rationale: Rationale for correct answer D: Levodopa therapy for Parkinson's disease has well-documented characteristics. A: Tolerance can develop to both beneficial effects (reduced over time) and adverse effects (increased over time). B: Levodopa is most effective in the initial years of treatment due to progressive loss of response. C: After 5 years, patients may experience dose-related dyskinesias, inadequate response, or toxicity due to disease progression and medication adjustments. Therefore, all statements are accurate and reflect the complexities of long-term levodopa therapy in Parkinson's disease.
Question 4 of 5
Indicate the pure opioid antagonist which has a half-life of 10 hours:
Correct Answer: B
Rationale: The correct answer is B: Naltrexone. Naltrexone is a pure opioid antagonist with a half-life of 10 hours, making it the most appropriate choice. Naloxone (A) is a short-acting opioid antagonist used for emergency overdose situations. Tramadol (C) is a weak opioid agonist with additional effects on serotonin and norepinephrine reuptake. Pentazocine (D) is a mixed opioid agonist-antagonist. Therefore, only Naltrexone fits the criteria of a pure opioid antagonist with a 10-hour half-life.
Question 5 of 5
Which of the following statements is true?
Correct Answer: D
Rationale: Rationale: - A: D1 receptors are indeed found in the striatum - B: D2 receptors are present in the striatum and limbic areas - C: D4 receptors are located in the frontal cortex and mesolimbic system Therefore, the correct answer is D as all statements are true, covering the distribution of D1, D2, and D4 receptors in the specified brain regions. Other choices are incorrect as they do not include all the correct statements.