ATI RN
Chapter 11 Cardiovascular Drugs Test Questions Quizlet Questions
Question 1 of 5
Which of the following agents inhibits hepatic metabolism of hypnotics?
Correct Answer: B
Rationale: The correct answer is B: Cimetidine. Cimetidine is a cytochrome P450 inhibitor that can inhibit hepatic metabolism of drugs like hypnotics, leading to increased drug levels and potential toxicity. Flumazenil (A) is a benzodiazepine receptor antagonist, not a metabolic inhibitor. Phenytoin (C) induces hepatic enzymes, increasing metabolism of other drugs. Theophylline (D) is metabolized by cytochrome P450, but it doesn't inhibit metabolism of hypnotics.
Question 2 of 5
Indicate a selective inhibitor of monoamine oxidase B:
Correct Answer: D
Rationale: The correct answer is D: Selegiline. Selegiline is a selective inhibitor of monoamine oxidase B (MAO-B), which helps increase dopamine levels in the brain. Levodopa is a precursor to dopamine, Amantadine is an antiviral drug used to treat Parkinson's symptoms, and Tolcapone is a COMT inhibitor. Selegiline specifically targets MAO-B without affecting MAO-A, making it the most suitable choice for selective inhibition of MAO-B in the context of Parkinson's disease treatment.
Question 3 of 5
It is undesirable to take alcohol before going outdoors when it extremely cold, but it may be harmless to take some after coming into a warm place from the cold.
Correct Answer: A
Rationale: The correct answer is A: TRUE. Alcohol consumption before going outdoors in extremely cold weather can lead to increased risk of hypothermia as it dilates blood vessels and causes heat loss. However, after coming indoors from the cold, having some alcohol may not pose the same risk as the body is already in a warm environment and can regulate its temperature better. Therefore, it is important to avoid alcohol before exposure to cold but may be harmless after being in a warm place. Choices B, C, and D are incorrect because they do not accurately reflect the specific considerations related to alcohol consumption in cold weather.
Question 4 of 5
Indicate the antipsychotic drug ,which is a thioxanthene derivative:
Correct Answer: D
Rationale: The correct answer is D: Thiothixene. Thiothixene is a thioxanthene derivative due to its chemical structure containing a thioxanthene ring system. Haloperidol, Clozapine, and Chlorpromazine are not thioxanthene derivatives. Haloperidol is a butyrophenone, Clozapine is a dibenzodiazepine, and Chlorpromazine is a phenothiazine. Therefore, the correct choice is D as it is the only antipsychotic drug among the options that belongs to the thioxanthene class based on its chemical structure.
Question 5 of 5
Indicate a tricyclic or a heterocyclic antidepressant having least antimuscarinic effects:
Correct Answer: D
Rationale: The correct answer is D: All of the above. Tricyclic and heterocyclic antidepressants like trazodone, bupropion, and mirtazapine have fewer antimuscarinic effects compared to older tricyclic antidepressants. These newer antidepressants have a more selective mechanism of action, targeting specific neurotransmitters, which leads to reduced antimuscarinic side effects like dry mouth, constipation, and blurred vision. Therefore, all three options have minimal antimuscarinic effects, making them favorable choices for patients who are sensitive to these side effects.