Which of the following agents helps in decreasing the frequency of vasoocclusive crises in children with sickle cell disease?

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ASCP Hematology Questions Questions

Question 1 of 5

Which of the following agents helps in decreasing the frequency of vasoocclusive crises in children with sickle cell disease?

Correct Answer: C

Rationale: Hydroxyurea (C) reduces vaso-occlusive crises by increasing fetal hemoglobin.

Question 2 of 5

One of the following features DOES NOT fit hemophilia A

Correct Answer: B

Rationale: Hemophilia A has normal PT (B incorrect); PTT is prolonged (C) due to low factor VIII (D).

Question 3 of 5

The BEST treatment option for factor VIII hemophiliacs with high titer inhibitor is

Correct Answer: D

Rationale: Recombinant factor VIIa (D) bypasses inhibitors, best for high-titer hemophilia A.

Question 4 of 5

Which of the following tests measures the step from fibrinogen to fibrin conversion?

Correct Answer: D

Rationale: Thrombin time (D) directly assesses fibrinogen to fibrin conversion.

Question 5 of 5

Deficiency of which of the following factors is asymptomatic?

Correct Answer: D

Rationale: Factor XII (E) deficiency doesn’t cause bleeding despite prolonged PTT.

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