Which of the following adverse effects is most likely to occur during the first days of lithium therapy?

Correct Answer: C

Rationale: Insomnia is a common early adverse effect of lithium therapy due to its impact on sleep patterns. Patients may experience difficulty falling asleep or staying asleep during the initial days of treatment. This side effect typically resolves as the body adjusts to the medication. Constipation, weight loss, hypertension, and edema are less commonly associated with lithium therapy in the early stages.

Correct Answer: C

Rationale: Bupropion is a medication that is commonly used to treat depression, ADHD, and smoking cessation. Given the woman's symptoms of feeling fearful, helpless, and worried, as well as her difficulty organizing thoughts and smoking habit, bupropion would be a suitable choice as it can address both depressive and attention deficit disorders, as well as aid in smoking cessation.

Correct Answer: D

Rationale: The opening of K+ channels on postsynaptic neurons is a key molecular action that mediates the analgesic effect of opioids like morphine. This action leads to hyperpolarization of the neuron, reducing its excitability and inhibiting pain transmission. Therefore, in a patient with severe pain due to multiple fractures, the opening of K+ channels by morphine would be the most likely mechanism responsible for the analgesic effect.

Correct Answer: D

Rationale: The patient self-injected what he believed to be heroin, which is commonly sold on the street. Fentanyl is a potent synthetic opioid that is often mixed with or sold as heroin due to its powerful effects. Therefore, the patient most likely took Fentanyl, as it is frequently associated with street drugs like heroin.

Correct Answer: A

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.