Which of the following actions is appropriate when managing a patient with a suspected heat stroke?

Correct Answer: D

Rationale: When managing a patient with a suspected heat stroke, the appropriate action is to remove the patient from the hot environment and start cooling the body. Heat stroke is a medical emergency that can be life-threatening if not promptly treated. Cooling the body is essential to lower the core body temperature as quickly as possible. Ice packs should not be directly applied to the skin as they can cause vasoconstriction and may actually hinder heat dissipation. Administering warm intravenous fluids and encouraging the patient to drink cold water rapidly are also not recommended in the initial management of a heat stroke. The priority is to cool the patient down and seek medical attention immediately.

Correct Answer: C

Rationale: Cervical intraepithelial neoplasia (CIN) is a premalignant condition of the cervix that is characterized by the presence of high-risk human papillomavirus (HPV) types. HPV infection is a major risk factor for the development of cervical cancer. CIN is typically detected on routine cervical screening tests such as Pap smears or HPV testing. If left untreated, CIN can progress to invasive cervical cancer. Therefore, the presence of high-risk HPV types in CIN lesions indicates an increased risk of developing cervical cancer.

Correct Answer: D

Rationale: In a 55-year-old postmenopausal woman presenting with vaginal bleeding and a healthy cervix on examination, the most likely cause would be a cervical polyp. Cervical polyps are benign growths that can occur on the cervix and are often asymptomatic but can occasionally cause postmenopausal bleeding. Their appearance on examination would typically be a non-malignant finding with no cervical motion tenderness. Cervical cancer, endometrial cancer, and vaginal cancer would typically present with different examination findings and risk factors.

Correct Answer: D

Rationale: A family history of breast cancer is a known risk factor for the development of ovarian cancer. Individuals with a close relative (such as a mother, sister, or daughter) who has had breast cancer have a higher risk of developing ovarian cancer. This increased risk is due to shared genetic factors that can predispose individuals to both breast and ovarian cancers. Therefore, having a family history of breast cancer is an important risk factor to consider in the assessment of ovarian cancer risk.

Correct Answer: B

Rationale: T cell exhaustion is a state of T cell dysfunction that arises during chronic viral infections or cancer. In the case of a chronic viral infection, the persistent exposure to viral antigens leads to continuous stimulation of CD8+ cytotoxic T cells. Over time, this sustained stimulation can lead to T cell exhaustion, characterized by the upregulation of inhibitory receptors, impaired effector functions, and reduced proliferative capacity. As a result, despite the elevated levels of CD8+ T cells in the blood, their function may be compromised, ultimately impacting the immune response against the viral infection. In contrast, activation-induced cell death (AICD) may contribute to T cell loss during chronic infections but would not explain the persistently elevated CD8+ T cell levels. Thymic involution refers to the age-related decline in thymus function, which is not directly related to the observed increase in CD8+ T cells. Antigenic