Which measure should be implemented for a child with von Willebrand disease who has a nosebleed?

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Question 1 of 5

Which measure should be implemented for a child with von Willebrand disease who has a nosebleed?

Correct Answer: A

Rationale: Applying firm pressure to the nose is the first-line intervention to control a nosebleed in von Willebrand disease.

Question 2 of 5

The main stay of treatment for congenital hypoplastic anemia is

Correct Answer: A

Rationale: Corticosteroids (A) are the mainstay for DBA, with ~70% response rate, unlike androgens (B, less effective), ATG (C, for aplastic anemia), or stem cell transplantation (D, E, reserved for non-responders).

Question 3 of 5

A 1-year-old child has folic acid deficiency since the age of 4 months, the best indicator of this deficiency is

Correct Answer: D

Rationale: Decreased RBC folate (D) directly measures folate stores, the best indicator. Elevated MCV (A) and hypersegmented neutrophils (E) are late signs, low reticulocytes (B) is nonspecific, and high LDH (C) reflects hemolysis, not folate-specific.

Question 4 of 5

Splenectomy is recommended in all the following conditions EXCEPT

Correct Answer: C

Rationale: Splenectomy is indicated for severe HS (A), elliptocytosis (B), thalassemia major (D), and refractory ITP (E). Hereditary stomatocytosis (C) often worsens post-splenectomy due to thrombosis risk, making it an exception.

Question 5 of 5

The best assessment of iron overload for patients with thalassemia major is achieved by

Correct Answer: A

Rationale: Liver MRI (A) accurately quantifies iron overload in thalassemia major, superior to ferritin (D, fluctuates), serum iron (C), TIBC (E), or invasive marrow biopsy (B).

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