ATI RN
Genitourinary System Assessment Questions
Question 1 of 5
Which macrolide antibiotic that can be given once a day for 3 days for * empirical treatment of ENT, respiratory and genital infections?
Correct Answer: B
Rationale: The correct answer is B: Azithromycin. It has a long half-life allowing for once-daily dosing for 3 days. Azithromycin is effective against common ENT, respiratory, and genital infections. Rationale: A: Erythromycin requires more frequent dosing due to shorter half-life. C: Clarithromycin is not typically given once a day for 3 days. D: Roxithromycin is less commonly used for these infections and has a shorter half-life.
Question 2 of 5
Which of the following antifungal agent act as fungicidal by inhibiting the * synthesis of β1,3 glucan used for the disseminated mucocutaneous Candida infections?
Correct Answer: A
Rationale: Rationale: Caspofungin is a echinocandin antifungal that inhibits the synthesis of β1,3 glucan in the fungal cell wall, leading to cell death. This mechanism makes it fungicidal against Candida infections. Amphotericin B disrupts fungal cell membranes, while Flucytosine interferes with DNA/RNA synthesis. Ketoconazole inhibits ergosterol synthesis. Therefore, A is correct as it targets the specific mechanism for Candida infections.
Question 3 of 5
A 75 year old male with BPH has continues to have urinary symptoms of * prostatic obstruction after trial of alpha blocking drug tamsulosin . Dutasteride is added to his therapy,he is also taking hydrochlorothiazide sildenafil and
Correct Answer: D
Rationale: The correct answer is D: Sildenafil. Dutasteride and sildenafil are both metabolized by the same enzymes in the liver, specifically CYP3A4 and CYP2C9. When taken together, sildenafil can increase the blood levels of dutasteride, leading to a higher risk of side effects. Tamsulosin (choice B) is commonly used in combination with dutasteride for BPH without significant interactions. Testosterone (choice C) is not typically used in BPH treatment and does not interact significantly with dutasteride. Therefore, the potential interaction between dutasteride and sildenafil is the reason why choice D is correct.
Question 4 of 5
A patient with severe infectious disease is being treated with aminoglycoside * antibiotics. Which of the following diuretic should be avoided for this patient because of the serious side effect shared by both drugs?
Correct Answer: A
Rationale: The correct answer is A: Furosemide. Aminoglycoside antibiotics can cause ototoxicity and nephrotoxicity. Furosemide, a loop diuretic, also has the potential to cause ototoxicity and nephrotoxicity, leading to a serious side effect when combined with aminoglycosides. On the other hand, choices B, C, and D (Hydrochlorothiazide, Spironolactone, and Acetazolamide) do not share the same serious side effects with aminoglycosides. Hydrochlorothiazide is a thiazide diuretic that acts on the distal convoluted tubule, Spironolactone is a potassium-sparing diuretic that acts on the collecting duct, and Acetazolamide is a carbonic anhydrase inhibitor diuretic that works in the proximal tubule. Therefore, Furosemide should
Question 5 of 5
Intravenous Plain NSS infusion is the treatment of choice for the following * complications of furosemide therapy:
Correct Answer: C
Rationale: Rationale: Intravenous Plain NSS infusion is the treatment of choice for dilutional hyponatremia, which can occur as a complication of furosemide therapy due to excessive diuresis leading to low sodium levels. This solution helps restore normal sodium levels without affecting the fluid balance. Summary: A: Hypokalemia - Furosemide therapy can cause hypokalemia, which is usually treated with potassium supplements, not NSS infusion. B: Severe dehydration - NSS infusion may be used for severe dehydration but is not specific to furosemide therapy complications. D: None of the above - Incorrect, as C is the correct answer for dilutional hyponatremia.