Which liver protein plays a key role in iron homeostasis?

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ASCP Hematology Questions Questions

Question 1 of 5

Which liver protein plays a key role in iron homeostasis?

Correct Answer: D

Rationale: Hepcidin (D) regulates iron absorption and storage, key to homeostasis.

Question 2 of 5

Which of the following agents helps in decreasing the frequency of vasoocclusive crises in children with sickle cell disease?

Correct Answer: C

Rationale: Hydroxyurea (C) reduces vaso-occlusive crises by increasing fetal hemoglobin.

Question 3 of 5

Which of the following conditions causes profound thrombocytopenia?

Correct Answer: A

Rationale: DIC (A) consumes platelets, causing profound thrombocytopenia.

Question 4 of 5

One of the following features DOES NOT fit hemophilia A

Correct Answer: B

Rationale: Hemophilia A has normal PT (B incorrect); PTT is prolonged (C) due to low factor VIII (D).

Question 5 of 5

The BEST treatment option for factor VIII hemophiliacs with high titer inhibitor is

Correct Answer: D

Rationale: Recombinant factor VIIa (D) bypasses inhibitors, best for high-titer hemophilia A.

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