Which laboratory test is ordered to determine the presence of the HIV antigen in an infant whose parent is HIV+?

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Question 1 of 5

Which laboratory test is ordered to determine the presence of the HIV antigen in an infant whose parent is HIV+?

Correct Answer: D

Rationale: A p24 antigen assay (or PCR/viral culture) is used to confirm HIV infection in infants.

Question 2 of 5

Anemia and reticulocytopenia that occur in the 2nd half of infancy period is LEAST likely due to

Correct Answer: A

Rationale: DBA (A) typically presents in the first 6 months, not later infancy (6-12 months), unlike TEC (B), prolonged hemolytic disease (C), aplastic crises (D), or Fanconi anemia (E), which can occur or persist into this period.

Question 3 of 5

Folic acid deficiency may develop in the following children EXCEPT

Correct Answer: C

Rationale: Goat’s milk (A), unfortified milk (B), phenytoin (D), and trimethoprim (E) impair folate intake or metabolism. Pasteurized cow’s milk (C) retains adequate folate, unlike unfortified formulas.

Question 4 of 5

In hereditary spherocytosis, all the following will resolve postsplenectomy EXCEPT

Correct Answer: A

Rationale: Splenectomy resolves anemia (B), reticulocytosis (C), hyperbilirubinemia (D), and aplastic crises (E) in HS by removing the site of RBC destruction. Osmotic fragility (A) persists, as it’s an intrinsic RBC defect.

Question 5 of 5

Blood transfusion therapy in a child with sickle cell anemia is indicated in all the following conditions EXCEPT

Correct Answer: C

Rationale: Transfusions are indicated for acute chest syndrome (A), stroke (B), and splenic sequestration (E) in sickle cell anemia to improve oxygenation or reduce sickle cells. Chronic pain (C) and avascular necrosis (D) are managed symptomatically, not with transfusion.

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