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free microbiology test bank questions pdf Questions
Question 1 of 9
Which is the most prominent immunoglobulin class present in external secretions
Correct Answer: C
Rationale: The correct answer is C: IgA. IgA is the most prominent immunoglobulin class present in external secretions like saliva, tears, and mucus. It plays a crucial role in mucosal immunity by preventing pathogens from entering the body. IgG is mainly found in the blood and tissues, IgM is the first antibody produced in response to an infection, and IgE is involved in allergic reactions. IgA's presence in external secretions helps protect the body from infections at mucosal surfaces, making it the correct choice in this context.
Question 2 of 9
The typical site for replication of DNA viruses is:
Correct Answer: A
Rationale: The correct answer is A: Nucleus. DNA viruses replicate in the host cell's nucleus because they require access to the host cell's DNA replication machinery. The nucleus contains the necessary enzymes and factors for DNA replication to occur accurately. The DNA viruses need to utilize these host cell components to replicate their own genetic material. Summary of why other choices are incorrect: B: Cytoplasm - Cytoplasm lacks the necessary enzymes and machinery for accurate DNA replication. C: Endoplasmic Reticulum - ER is involved in protein synthesis and processing, not DNA replication. D: Golgi Apparatus - Golgi apparatus is responsible for processing and packaging proteins, not DNA replication.
Question 3 of 9
Which type of bacteria can survive in extreme salty environments?
Correct Answer: B
Rationale: The correct answer is B: Halophiles. Halophiles are bacteria that can survive in extreme salty environments. They have adapted to thrive in high salt concentrations. Psychrophiles (A) thrive in cold temperatures, Thermophiles (C) thrive in high temperatures, and Mesophiles (D) thrive in moderate temperatures. Therefore, they are not adapted to survive in extreme salty environments like Halophiles.
Question 4 of 9
The causative agent of tuberculosis is:
Correct Answer: B
Rationale: The correct answer is B: Mycobacterium tuberculosis. Mycobacterium tuberculosis is the causative agent of tuberculosis, as it specifically infects the lungs and can spread to other parts of the body. Mycobacterium leprae (Choice A) causes leprosy, not tuberculosis. Bacillus anthracis (Choice C) causes anthrax, not tuberculosis. Staphylococcus aureus (Choice D) is a common bacterium known for causing skin infections, not tuberculosis. Therefore, Mycobacterium tuberculosis is the correct answer for the causative agent of tuberculosis.
Question 5 of 9
Acne is caused by:
Correct Answer: D
Rationale: The correct answer is D: Propionibacterium acnes. This bacterium plays a key role in acne formation by colonizing hair follicles, leading to inflammation and acne lesions. It produces fatty acids that contribute to the development of acne. Staphylococcus aureus (A) and Staphylococcus epidermidis (B) are not directly linked to acne. Streptococcus pyogenes (C) is associated with skin infections but not acne. In summary, Propionibacterium acnes is the primary bacterium responsible for acne due to its ability to induce inflammation and follicular blockages.
Question 6 of 9
The bacteria responsible for anthrax is:
Correct Answer: A
Rationale: The correct answer is A: Bacillus anthracis. This bacterium is known to cause anthrax, a serious infectious disease in humans and animals. Bacillus anthracis is a gram-positive, spore-forming bacterium that produces toxins leading to the characteristic symptoms of anthrax. Clostridium tetani causes tetanus, Mycobacterium tuberculosis causes tuberculosis, and Streptococcus pneumoniae causes pneumonia, none of which are related to anthrax. Therefore, based on the specific pathogen responsible for anthrax, Bacillus anthracis is the correct answer.
Question 7 of 9
A patient complains of frequent bowel movements and stool with blood admixtures ("raspberry jelly" stool). Microscopic examination revealed large mononuclear cells with absorbed red blood cells. What protozoon is this morphological structure typical for?
Correct Answer: A
Rationale: The correct answer is A: Entamoeba histolytica. This protozoon is responsible for causing amoebic dysentery, which presents with bloody diarrhea. The "raspberry jelly" appearance of stool is due to the presence of mucosal lining and blood. The large mononuclear cells with absorbed red blood cells are characteristic of the histopathology of Entamoeba histolytica infection. Giardia lamblia (B) causes watery diarrhea, not bloody stools. Campylobacter jejuni (C) is a bacterial pathogen associated with gastroenteritis, but does not typically cause bloody diarrhea. Toxoplasma gondii (D) causes toxoplasmosis, a systemic infection with symptoms such as fever and lymphadenopathy, but not bloody diarrhea.
Question 8 of 9
The class of immunoglobulins most abundant in body is:
Correct Answer: A
Rationale: The correct answer is A: IgG. IgG is the most abundant class of immunoglobulins in the body, constituting about 75% of total immunoglobulins. IgG plays a crucial role in long-term immunity, neutralizing toxins, and enhancing phagocytosis. IgE is involved in allergic reactions, IgD is mainly found on B cells and functions as a receptor, and IgM is the first antibody produced in response to an infection but is less abundant compared to IgG. Therefore, IgG is the correct choice based on its abundance and diverse functions in the immune system.
Question 9 of 9
Which bacterium is responsible for causing pneumonia?
Correct Answer: A
Rationale: The correct answer is A: Streptococcus pneumoniae. This bacterium is the most common cause of bacterial pneumonia in adults. It is a leading cause of community-acquired pneumonia. Streptococcus pneumoniae is known for its ability to infect the respiratory tract and cause inflammation in the lungs leading to pneumonia. Mycobacterium tuberculosis causes tuberculosis, not pneumonia. Escherichia coli is associated with urinary tract infections and gastrointestinal illnesses, not pneumonia. Clostridium botulinum causes botulism, a severe form of food poisoning, but not pneumonia. Therefore, the correct choice is Streptococcus pneumoniae as it is specifically known for causing pneumonia.