ATI RN
Pediatric Immunization Practice Questions Questions
Question 1 of 5
Which is the most common defined immunodeficiency disorder?
Correct Answer: B
Rationale: Selective IgA deficiency is the most common primary immunodeficiency, often asymptomatic but can lead to recurrent infections or allergies.
Question 2 of 5
A 13-month-old male presented with vomiting, fever, and irritability. On examination his temperature was 40°C, lethargic, with atrophied tonsils, clear tympanic membrane, clear chest and neck stiffness. The parents gave past history of pneumonia at the age of 6 and 9 months for which he was admitted to hospital and treated with i.v. antibiotics for 10 days. Of the following, the MOST likely diagnosis is
Correct Answer: A
Rationale: Recurrent bacterial infections and absent tonsils suggest agammaglobulinemia, likely X-linked, due to severe B-cell deficiency.
Question 3 of 5
An 18-month-old male child presented with failure to thrive and chronic diarrhea. On examination he has dermatitis, generalized lymphadenopathy, hepatosplenomegaly, and deep seated infection in the inguinal area. His lab. investigations revealed anemia and hypergammaglobulinemia. Of the following, the MOST likely diagnosis is
Correct Answer: D
Rationale: Chronic granulomatous disease causes failure to thrive, deep infections, and hypergammaglobulinemia due to defective phagocyte killing.
Question 4 of 5
Which of the following regulators inhibits C3convertase
Correct Answer: D
Rationale: CD46 (membrane cofactor protein) inhibits C3 convertase by promoting its degradation, regulating the complement system to prevent excessive activation.
Question 5 of 5
Wrong about antigen interaction with lymphocytes
Correct Answer: C
Rationale: T cells recognize antigens only when presented on MHC molecules by antigen-presenting cells, not as soluble antigens directly.