Which immune system cells recognize body cells with reduced expression of MHC class I molecules?

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Pediatric Immunity NCLEX Questions Questions

Question 1 of 5

Which immune system cells recognize body cells with reduced expression of MHC class I molecules?

Correct Answer: D

Rationale: NK cells target cells with low MHC I, a sign of viral infection or malignancy.

Question 2 of 5

In addition to infection and bleeding, the MOST common cause of death in Wiskott-Aldrich syndrome is

Correct Answer: D

Rationale: Wiskott-Aldrich syndrome (WAS) patients have a high risk of EBV-associated lymphomas due to immune dysregulation, making it a leading cause of death.

Question 3 of 5

Chronic neutropenia by definition lasts longer than

Correct Answer: B

Rationale: Chronic neutropenia is defined as lasting >3 months, distinguishing it from transient causes like viral infections.

Question 4 of 5

Shifting to the left (proportion of immature neutrophil cells >5%) may occasionally be caused by all the following EXCEPT

Correct Answer: D

Rationale: Megaloblastic anemia affects RBC production, not neutrophil maturation; the others cause stress-induced left shifts.

Question 5 of 5

The complement component of both the classical and alternative pathways is

Correct Answer: B

Rationale: C3 is central to both classical and alternative pathways, acting as a convergence point for complement activation.

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