ATI RN
Pharmacology Final ATI Questions
Question 1 of 5
Which drug is used to reverse the effects of an opioid overdose?
Correct Answer: C
Rationale: Naloxone is a medication used to reverse the effects of an opioid overdose. It works by binding to the opioid receptors in the brain, displacing the opioids and temporarily reversing their effects. Naloxone is commonly administered in emergency situations to quickly restore normal breathing and consciousness in individuals who have overdosed on opioids. Aspirin (choice A) and Advil (choice B) are non-opioid pain relievers and do not reverse the effects of an opioid overdose. Ondansetron (choice D) is an anti-nausea medication and does not counteract the respiratory depression caused by opioid overdose.
Question 2 of 5
A client who is receiving edrophonium chloride suddenly is complaining of abdominal cramps and the nurse observes the client is experiencing increased perspiration and salivation. The nurse makes sure the availability of which of the following?
Correct Answer: C
Rationale: Edrophonium chloride is a medication used to diagnose myasthenia gravis, a condition characterized by muscle weakness. When a client receiving edrophonium chloride suddenly experiences symptoms like abdominal cramps, increased perspiration, and salivation, these are suggestive of cholinergic crisis, which is an overdose of acetylcholinesterase inhibitors like edrophonium. Atropine sulfate is an anticholinergic medication used to counteract the effects of excessive acetylcholine in the body, hence it is essential to have it readily available to manage cholinergic crisis in this client. Levodopa, methylphenidate hydrochloride, and carbamazepine are not indicated for managing cholinergic crisis.
Question 3 of 5
Drugs with no significant effect on anticoagulant therapy include:
Correct Answer: D
Rationale: Amiodarone inhibits warfarin metabolism, increasing INR, so it affects anticoagulation. Disulfiram also potentiates warfarin via CYP inhibition, enhancing effect. Fluconazole similarly boosts warfarin levels, a significant interaction. Benzodiazepines have no major effect on anticoagulant therapy, a true statement, as they're metabolized differently. Metronidazole, like fluconazole, increases warfarin effect. Benzodiazepines' lack of interaction makes them safer in this context, a key consideration in polypharmacy.
Question 4 of 5
The patient receives imipramine (Tofranil) as treatment for depression. He is admitted to the emergency department following an intentional overdose of this medication. What will the priority assessment by the nurse include?
Correct Answer: A
Rationale: Imipramine, a tricyclic antidepressant, is cardiotoxic in overdose, causing dysrhythmias (e.g., widened QRS) due to sodium channel blockade. The priority assessment is cardiac status to detect life-threatening arrhythmias, guiding urgent interventions like sodium bicarbonate. Liver and renal effects are secondary in acute overdose. Neurological issues like seizures occur but are less immediately lethal than cardiac collapse. The nurse focuses on cardiac monitoring, aligning with toxicology priorities, making A the critical assessment.
Question 5 of 5
When teaching a patient about antihypertensive drug therapy, which statements by the nurse are correct? (Select all that apply.)
Correct Answer: A
Rationale: A. You need to have your blood pressure checked once a week and keep track of the readings. - This is correct because monitoring blood pressure regularly is essential to assess the effectiveness of antihypertensive drug therapy and make any necessary adjustments.