ATI RN
Pharmacology ATI Final Questions
Question 1 of 5
Which common adverse effects of selective serotonin reuptake inhibitors (SSRIs) would be stressed by the nurse during patient discharge?
Correct Answer: B
Rationale: SSRIs (e.g., sertraline) commonly cause weight gain and sexual dysfunction (e.g., delayed ejaculation), per patient reports-key for adherence. Drowsiness/coma are overdose risks, not common. Headache/nausea occur but fade. Dry mouth/urine retention are anticholinergic, not SSRI. These impact quality of life, needing emphasis.
Question 2 of 5
A 26-year-old man with a chronic cough takes codeine for cough suppression. He presents to his primary care physician for follow-up. The patient admits to taking this medication three times daily even when he does not have symptoms. The treating physician must be concerned about which of the following effects?
Correct Answer: A
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 3 of 5
A 34-year-old man presents to the emergency department with fevers, chills, muscle aches, and headaches for the past 16 h. His son has been sick for the past week and unable to attend daycare. He did not receive the influenza vaccine this year. A nasal swab is performed and he is diagnosed with influenza. He is started on oseltamivir. What is the mechanism of action of oseltamivir?
Correct Answer: C
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 4 of 5
A patient suffering from attention deficit hyperactivity disorder is placed on atomoxetine. A drug that has a similar mechanism of action to atomoxetine is
Correct Answer: D
Rationale: Atomoxetine treats ADHD by selectively inhibiting norepinephrine (NE) reuptake, increasing NE and dopamine in the prefrontal cortex to improve attention and impulse control, without stimulant properties. Methylphenidate blocks DA and NE reuptake but is a stimulant, differing in profile and abuse potential. Botulinum toxin affects neuromuscular junctions, unrelated to ADHD. Clonidine, an alpha-2 agonist, reduces NE release, calming hyperactivity but not via reuptake. Amitriptyline, a TCA, inhibits NE and 5HT reuptake, with broader effects and sedation, used off-label for ADHD in some cases. Its NE reuptake inhibition parallels atomoxetine's core mechanism, though it's less selective and not first-line. Among these, amitriptyline's shared NE focus makes it mechanistically closest.
Question 5 of 5
The patient receives imipramine (Tofranil) as treatment for depression. He is admitted to the emergency department following an intentional overdose of this medication. What will the priority assessment by the nurse include?
Correct Answer: A
Rationale: Imipramine, a tricyclic antidepressant, is highly cardiotoxic in overdose, often causing fatal dysrhythmias due to sodium channel blockade, leading to widened QRS complexes and ventricular arrhythmias. The priority assessment must focus on cardiac status to detect life-threatening changes like tachycardia or arrhythmias, requiring immediate intervention such as sodium bicarbonate or cardioversion. Liver function and renal status may be affected long-term but aren't the acute priority in overdose. Neurological function , while impacted (e.g., seizures), is secondary to cardiac risks, as circulatory collapse poses the greatest immediate threat. The nurse's focus on cardiac monitoring aligns with toxicology protocols, ensuring rapid response to the most lethal complication, making choice A the critical assessment in this emergency scenario.