ATI RN
Chemotherapy drugs Questions
Question 1 of 5
Which cell involved in immune function recognizes foreign peptides bound of MHC class II molecules on the surface of APC cells, secretes interleukin-2, and initiates the cell-mediated immunity reaction responsible for host-versus-graft reactions?
Correct Answer: D
Rationale: T-helper (TH) lymphocytes recognize MHC class II-bound peptides, secrete IL-2, and initiate cell-mediated immunity, including host-versus-graft reactions.
Question 2 of 5
Which one of the following agents is able to suppress both B and T lymphocytes via its inhibition of de novo synthesis of purines?
Correct Answer: C
Rationale: Mycophenolate mofetil inhibits inosine monophosphate dehydrogenase, blocking de novo purine synthesis and suppressing both B and T lymphocytes.
Question 3 of 5
In the treatment of acute inorganic arsenic poisoning, the most likely drug to be used is
Correct Answer: B
Rationale: Dimercaprol (BAL) is the drug of choice for acute arsenic poisoning as it chelates arsenic, promoting its excretion.
Question 4 of 5
A businessman intends to travel abroad in a geographical region where several diseases are endemic. He would not be able to be vaccinated against
Correct Answer: B
Rationale: There is no vaccine for malaria; prophylaxis relies on antimalarial drugs, unlike the other diseases listed which have vaccines.
Question 5 of 5
A needlestick injury is sustained by a health care worker, and the blood is known to contain HBV surface antigens. The health care worker should be given
Correct Answer: D
Rationale: Post-exposure prophylaxis for HBV includes both hepatitis B vaccine (active immunity) and hepatitis B immune globulin (passive immunity) for immediate and long-term protection.