ATI RN
Drugs Affecting the Cardiovascular and Renal Systems Edapt Quizlet Questions
Question 1 of 5
Which category of histamine H1 antagonists is noted for the best antiemetic action?
Correct Answer: C
Rationale: The correct answer is C: Piperazines; i.e. Hydroxyzine, Cyclizine. Piperazine-based H1 antagonists have the best antiemetic action due to their strong anticholinergic properties, which help in reducing nausea and vomiting. Hydroxyzine and Cyclizine specifically are known for their effectiveness in combating motion sickness and nausea. Alkylamines (A), Ethanolamines (B), and Ethylenediamines (D) are not as effective in treating nausea and vomiting compared to piperazines due to their weaker anticholinergic effects.
Question 2 of 5
Very low density lipoprotein (VLDL) is:
Correct Answer: A
Rationale: Correct Answer: A Rationale: 1. VLDL is a lipoprotein containing a very large proportion of lipids to protein. 2. It carries cholesterol from the liver to the tissues. 3. VLDL is a precursor to LDL, carrying triglycerides and cholesterol. 4. Choice A correctly describes the characteristics and function of VLDL. Summary: - Choice B is incorrect as it describes LDL, not VLDL. - Choice C is incorrect as it describes HDL, not VLDL. - Choice D is incorrect as it describes chylomicrons, not VLDL.
Question 3 of 5
Gout is a familial metabolic disease characterized by recurrent episodes of acute arthritis due to deposits of monosodium urate in joints and cartilage. This consideration is:
Correct Answer: A
Rationale: The correct answer is A: TRUE. Gout is indeed a familial metabolic disease characterized by acute arthritis caused by monosodium urate deposits in joints. The term "familial" indicates a genetic predisposition to the condition. Choice B is incorrect because gout is not a random occurrence but rather a metabolic disorder. Choice C, "All," is incorrect as it implies that every possible consideration about gout is true, which is not the case. Choice D, "None," is also incorrect as there are specific characteristics and features associated with gout that make it distinguishable from other conditions.
Question 4 of 5
Correct statements about etidronate include all of the following, EXCEPT:
Correct Answer: C
Rationale: The correct answer is C because etidronate is actually a 1st generation biphosphonate, not a 2nd generation one. The skeletal half-life of etidronate is short, not hundreds of days like option A suggests. Bioavailability of etidronate decreases with the administered dose, making option B incorrect. In summary, etidronate is a 1st generation biphosphonate with a short skeletal half-life and decreasing bioavailability with higher doses.
Question 5 of 5
The drug is usually given in combination with a thiazide diuretic:
Correct Answer: D
Rationale: The correct answer is D: Amiloride (Midamor). Amiloride is typically given in combination with a thiazide diuretic to counteract potassium loss caused by thiazides. Thiazides like Hydrochlorothiazide (Choice C) and loop diuretics like Furosemide (Choice B) can lead to hypokalemia, which is why amiloride is used to spare potassium. Acetazolamide (Choice A) is a carbonic anhydrase inhibitor and is not typically combined with thiazide diuretics for potassium-sparing effects.