Which bacteria is responsible for causing tuberculosis?

Correct Answer: A

Rationale: The correct answer is A: Mycobacterium tuberculosis. This bacterium is responsible for causing tuberculosis. It is a slow-growing, acid-fast bacillus that primarily affects the lungs. Mycobacterium tuberculosis is transmitted through the air via respiratory droplets. Choice B, Streptococcus pneumoniae, is a common cause of pneumonia but not tuberculosis. Choice C, Salmonella enterica, causes food poisoning. Choice D, Neisseria meningitidis, causes meningitis, not tuberculosis. Therefore, Mycobacterium tuberculosis is the correct answer based on its characteristics and mode of transmission.

Correct Answer: A

Rationale: The presence of rods with polar dark blue granules stained by Neisser's method indicates metachromatic granules consistent with Corynebacterium diphtheriae. The characteristic staining pattern is due to the presence of polar granules in the bacterial cells, a feature specific to Corynebacterium diphtheriae. Bacillus anthracis, Clostridium tetani, and Escherichia coli do not exhibit this staining pattern or morphology typical of Corynebacterium diphtheriae, making them incorrect choices.

Correct Answer: A

Rationale: The correct answer is A: Selective toxicity. Chemotherapy aims to target cancer cells while minimizing harm to healthy cells, known as selective toxicity. This principle is crucial to effectively treat cancer without causing excessive damage to the patient's body. Accumulation in the macroorganism (B) and causing allergies (C) are not fundamental principles of chemotherapy and can lead to harmful side effects. Therefore, the correct answer is A as it aligns with the core objective of chemotherapy.

Correct Answer: D

Rationale: The correct answer is D: epidermolytic toxin. This toxin specifically targets the epidermis, leading to exfoliation seen in scalded skin syndrome (SSS). Hemolysis (A) refers to the destruction of red blood cells, not relevant to SSS. Enterotoxins (B) cause food poisoning, not SSS. Leucocidins (C) target white blood cells, not pertinent to SSS. Therefore, the epidermolytic toxin (D) is the correct choice for causing SSS.

Correct Answer: A

Rationale: The correct answer is A: Entamoeba histolytica. This protozoan causes amoebiasis, which presents with symptoms like diarrhea. The cysts with four nuclei found in the feces are characteristic of Entamoeba histolytica. This protozoan is known to cause invasive infection, leading to tissue destruction and ulcers in the intestines. Lamblia (choice B) typically presents with cysts containing two nuclei. Trichomonas (choice C) is a sexually transmitted parasite and does not form cysts. Balantidium (choice D) is a ciliated protozoan that does not have four nuclei in its cyst form.

Correct Answer: B

Rationale: The Gram stain differentiates bacteria based on cell wall structure. It classifies bacteria into Gram-positive (purple) and Gram-negative (pink) based on the presence of peptidoglycan in the cell wall. This method helps in identifying the bacterial species and determining appropriate treatment. Option A (Cell shape) is incorrect because the Gram stain focuses on cell wall composition, not cell shape. Option C (Flagella composition) is incorrect as the Gram stain does not assess flagella. Option D (Nutrient requirements) is incorrect as it does not relate to the purpose of the Gram stain.

Correct Answer: B

Rationale: The correct answer is B: Mycobacterium tuberculosis. This bacterium is responsible for causing tuberculosis. Mycobacterium leprae (choice A) causes leprosy, not tuberculosis. Streptococcus pneumoniae (choice C) is known for causing pneumonia, not tuberculosis. Neisseria gonorrhoeae (choice D) is responsible for causing gonorrhea, not tuberculosis. Mycobacterium tuberculosis is the specific bacterium associated with tuberculosis due to its ability to infect the lungs and other organs, leading to the characteristic symptoms of the disease.

Correct Answer: D

Rationale: Production of auto-antibodies can be due to various factors. Mutant B cell clones can lead to the production of self-reactive antibodies. Antibodies against hidden tissues can also trigger autoimmune responses. Genetic factors play a crucial role in predisposing individuals to autoimmunity. Therefore, the correct answer is D, as all these factors can contribute to the production of auto-antibodies. Choice A is incorrect as it only addresses one possible cause. Choice B is incorrect as it focuses solely on antibodies against hidden tissues. Choice C is incorrect as it overlooks the other potential reasons for auto-antibody production.

Correct Answer: A

Rationale: The correct answer is A: Corynebacterium diphtheriae. This bacterium produces the diphtheria toxin, which is responsible for causing diphtheria. The other choices, B, C, and D, are incorrect because Bacillus anthracis produces anthrax toxins, Clostridium tetani produces tetanus toxin, and Listeria monocytogenes does not produce the diphtheria toxin. Understanding the specific bacteria-toxin associations is crucial in correctly identifying the pathogen responsible for a particular disease.