Which bacteria is responsible for causing the disease known as leprosy?

Correct Answer: A

Rationale: The correct answer is A: Mycobacterium leprae. This bacterium is responsible for causing leprosy. Mycobacterium leprae is a slow-growing bacterium that affects the skin and nerves, leading to the characteristic symptoms of leprosy. Neisseria gonorrhoeae is a sexually transmitted bacterium causing gonorrhea. Streptococcus pneumoniae causes pneumonia and other respiratory infections. Clostridium perfringens is associated with food poisoning and gas gangrene. Therefore, the correct answer is A because Mycobacterium leprae specifically causes leprosy, while the other choices are associated with different diseases.

Correct Answer: A

Rationale: The correct answer is A: Clostridium perfringens. This bacterium is an anaerobic, Gram-positive rod that forms terminal spores and produces gas. It is commonly associated with wound infections and gas gangrene. Clostridium botulinum causes botulism and does not typically present with gas production. Bacillus anthracis is an aerobic, Gram-positive spore-forming bacterium causing anthrax. Clostridium tetani causes tetanus and does not produce gas. Thus, based on the characteristics described in the question, Clostridium perfringens is the most likely causative agent.

Correct Answer: C

Rationale: 1. OSHA stands for Occupational Safety and Health Administration. 2. OSHA is responsible for ensuring safe and healthy working conditions in the US. 3. The U.S. Department of Labor oversees OSHA's operations and regulations. 4. Therefore, the correct answer is C, as OSHA is a division of the U.S. Department of Labor. 5. Other choices are incorrect because they are not directly related to OSHA's jurisdiction or responsibilities.

Correct Answer: C

Rationale: Rationale: 1. Psychrophilic: Grow best in cold temperatures 2. Mesophilic: Grow best in moderate temperatures 3. Thermophilic: Grow best in high temperatures - Choice A is incorrect as "thermophobic" is not a recognized term. - Choice B is incorrect as "psychophobic" is not a recognized term. - Choice D is incorrect as "mesophobic" is not a recognized term.

Correct Answer: B

Rationale: Step-by-step rationale: 1. Filamentous spiral nucleocapsid is characteristic of Filoviridae, such as Ebola virus. 2. Linear unsegmented single strand (-) RNA is a key feature of Filoviridae genomes. 3. The lipid bilayer membrane of cellular origin is found in Filoviridae viruses. 4. Therefore, the correct answer is B (Filoviridae) due to the alignment of all three morphological features. Summary: - A (Picornaviridae): Has an icosahedral capsid, not filamentous spiral. - C (Orthomyxoviridae): Has a segmented genome, not linear unsegmented. - D (Togaviridae): Has a spherical capsid, not filamentous spiral.

Correct Answer: D

Rationale: The correct answer is D: Terminally. In Clostridium tetani, spores are located at the terminal end of the cell. This positioning helps the spores to be released easily when the cell lyses, aiding in the spread of the bacteria. Paracentrally (A) and centrally (C) would not be as efficient for spore release. Subterminally (B) is also incorrect as the spores are specifically located at the terminal end of the cell, not just near it.

Correct Answer: A

Rationale: The correct answer is A: Pseudomonas aeruginosa. Pseudomonas aeruginosa is a gram-negative bacterium known for its green-blue pigmentation and sweet, fruity odor. The large colorless mucous colonies that develop green-blue pigmentation and honey or jasmine smell point towards Pseudomonas aeruginosa. The bacterioscopy revealing gram-negative lophotrichea further supports this identification. Proteus vulgaris and Klebsiella osaenae do not typically exhibit the described characteristics. Streptomyces griseus is a soil bacterium known for its antibiotic production and is not commonly associated with wound infections.

Correct Answer: A

Rationale: Exotoxins are proteins produced inside the microbe cell and then released outside the cell to exert their toxic effects on neighboring cells or tissues. This is why choice A is correct. Choices B and C are incorrect because exotoxins are not meant to act within the same cell they are produced in. Choice D is incorrect because exotoxins are usually released without causing cell lysis; they are secreted by the microbe actively rather than being leaked out due to cell damage.

Correct Answer: B

Rationale: The correct answer is B: pertussis toxin. This toxin is the most important virulence factor of Bordetella pertussis because it plays a key role in causing the characteristic symptoms of whooping cough. Pertussis toxin interferes with the host's immune response, leading to inflammation and tissue damage in the respiratory tract. The other choices (A: the flagellum, C: P fimbriae, D: mannose-resistant adhesins) are important for bacterial attachment and colonization, but they do not directly contribute to the severity of the disease like pertussis toxin does.