Which bacteria are responsible for causing the disease known as syphilis?

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Question 1 of 5

Which bacteria are responsible for causing the disease known as syphilis?

Correct Answer: A

Rationale: The correct answer is A: Treponema pallidum. This bacterium is responsible for causing syphilis due to its unique spiral shape and ability to penetrate intact mucous membranes. It is transmitted through sexual contact or from mother to child during pregnancy. Neisseria gonorrhoeae causes gonorrhea, Chlamydia trachomatis causes chlamydia, and Escherichia coli is a common bacterium found in the gut and not associated with syphilis. Treponema pallidum's specific characteristics and mode of transmission distinguish it from the other choices, making it the correct answer.

Question 2 of 5

Which of the following bacteria produce endotoxins that can lead to septic shock?

Correct Answer: D

Rationale: The correct answer is D because all three bacteria listed (Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa) can produce endotoxins that can lead to septic shock. Endotoxins are lipopolysaccharides found in the outer membrane of Gram-negative bacteria like E. coli and P. aeruginosa. Staphylococcus aureus, a Gram-positive bacterium, can also produce endotoxins called superantigens that can trigger a massive immune response leading to septic shock. Therefore, all of the above choices are correct. Choices A, B, and C alone are incorrect because they do not account for the fact that all three bacteria listed produce endotoxins that can cause septic shock.

Question 3 of 5

Agglutination reaction is one of the following

Correct Answer: A

Rationale: The correct answer is A: Ascoli ring test. Agglutination reaction in the Ascoli ring test is characterized by the formation of a visible ring at the interface of antigen and antibody. This reaction specifically tests for the presence of specific antibodies against antigens in serum, indicating a recent or current infection. The other options, Western blot, ELISA, and Reaction type Gruber, do not involve the agglutination reaction. Western blot and ELISA are immunoassay techniques that detect specific antibodies or antigens, while Reaction type Gruber is not a recognized method in immunology. Therefore, the Ascoli ring test is the correct choice for a test involving agglutination reaction.

Question 4 of 5

Which statement related to the mumps vaccine is true:

Correct Answer: D

Rationale: The correct answer is D: it is a live attenuated vaccine. This is true because the mumps vaccine is indeed a live attenuated vaccine, meaning it contains a weakened form of the virus to stimulate an immune response without causing the disease. This type of vaccine provides long-lasting immunity. A, B, and C are incorrect: A: the vaccine is recommended, not obligatory - this is incorrect because the mumps vaccine is typically recommended for all individuals to prevent the spread of the disease. B: the vaccine is not given in combination with other vaccines - this is incorrect as the mumps vaccine is often given in combination with measles and rubella vaccines as the MMR vaccine. C: the vaccine is administered orally - this is incorrect because the mumps vaccine is usually administered via injection, not orally.

Question 5 of 5

An adult patient with type 2 diabetes attends the emergency room. He reported that two days ago he was accidentally injured in the left leg, but he did not seek medical care. At the time of examination, an infected wound was found, surrounded by a large area of inflammation with characteristic tissue crepitation on palpation and with foul odor. Blood (for hemoculture) and wound secretions were taken for microbiological testing. The microscopic examination reveals large Gram-positive bacteria, with centrally located spores. These bacteria were unable to grow in vitro at presence of oxygen. The most likely cause of this disease is:

Correct Answer: B

Rationale: The correct answer is B: Clostridium perfringens. In this case, the patient's presentation of infected wound with tissue crepitation, foul odor, and Gram-positive bacteria with centrally located spores that cannot grow in the presence of oxygen is indicative of gas gangrene caused by Clostridium perfringens. This anaerobic bacterium produces various toxins that lead to tissue destruction and gas production in the affected area. Clostridium tetani (choice A) causes tetanus, characterized by muscle stiffness and spasms. Clostridium botulinum (choice C) causes botulism, leading to muscle paralysis. Clostridium difficile (choice D) is associated with antibiotic-associated diarrhea. These choices are incorrect as they do not match the clinical presentation described in the question.

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