Which bacteria are responsible for causing meningitis?

Correct Answer: D

Rationale: The correct answer is D. Neisseria meningitidis, Haemophilus influenzae, and Streptococcus pneumoniae are all known to cause meningitis. Neisseria meningitidis is a common cause of bacterial meningitis in young adults. Haemophilus influenzae is a leading cause of meningitis in children, and Streptococcus pneumoniae is a common cause in adults. Therefore, all three bacteria are responsible for causing meningitis, making option D the correct choice. Option A, B, and C are incorrect because they each represent only one of the bacteria responsible for causing meningitis, while option D includes all three.

Correct Answer: B

Rationale: The correct answer is B: peak effect. When drug receptors are maximally activated, it means the drug has reached its highest effectiveness, resulting in the peak effect. This occurs when the drug concentration is at its highest level in the body, leading to the maximum response. Threshold level (A) refers to the minimum amount of drug needed to produce a response. Cessation effect (C) is when the drug's effect wears off. Latency time (D) is the time it takes for the drug to start producing an effect. So, the peak effect best describes the scenario where drug receptors are maximally activated.

Correct Answer: A

Rationale: The correct answer is A: Pseudomonas aeruginosa. Pseudomonas aeruginosa is known to produce green colonies on Endo agar due to its pyoverdin pigment. It is also a Gram-negative rod. P. aeruginosa commonly causes respiratory infections in immunocompromised patients. Escherichia coli (B) typically produces pink colonies on Endo agar and is more associated with gastrointestinal infections. Salmonella typhi (C) and Shigella dysenteriae (D) are both Enterobacteriaceae that usually do not produce green colonies on Endo agar and are more associated with gastrointestinal infections as well.

Correct Answer: D

Rationale: The correct answer is D because Borrelia burgdorferi cannot be detected with Giemsa stain. Giemsa stain is commonly used to visualize blood smears for malaria parasites but is not effective for Borrelia burgdorferi detection. A: Borrelia burgdorferi can be cultivated on blood agar - This is correct. Borrelia burgdorferi can be grown in culture on a special medium like Barbour-Stoenner-Kelly (BSK) agar. B: Borrelia burgdorferi is flexible, motile spirochete - This is correct. Borrelia burgdorferi is a spiral-shaped bacterium that moves using a corkscrew motion. C: Borrelia burgdorferi is transmitted by arthropods- ticks - This is correct. Borrelia burgdorferi is primarily transmitted to humans through the bite of infected ticks, particularly Ixodes

Correct Answer: A

Rationale: Step-by-step rationale: 1. Mycobacterium tuberculosis is the causative agent of tuberculosis. 2. Mycobacterium tuberculosis is a slow-growing, acid-fast bacterium. 3. It primarily infects the lungs and can spread to other parts of the body. 4. Bacillus anthracis causes anthrax, Clostridium tetani causes tetanus, and Treponema pallidum causes syphilis. 5. Therefore, choice A, Mycobacterium tuberculosis, is the correct answer for the bacteria responsible for tuberculosis.

Correct Answer: B

Rationale: The correct answer is B: Aminoglycosides. Aminoglycosides are antibiotics that act by binding to the 30S ribosomal subunit, disrupting protein synthesis in bacteria. This interaction affects the ribosomes directly, leading to inhibition of bacterial protein production. Penicillins (A) work by inhibiting cell wall synthesis, Sulfonamides (C) target folic acid synthesis, and Quinolones (D) inhibit DNA gyrase. These mechanisms do not directly affect the ribosomes, making them incorrect choices in this context.

Correct Answer: A

Rationale: The correct answer is A: BCG vaccine. Step 1: BCG vaccine is specifically designed to protect against tuberculosis, making it the appropriate choice for newborns. Step 2: STI vaccine is for sexually transmitted infections, not tuberculosis. Step 3: EV vaccine is not a recognized vaccine. Step 4: DPT vaccine protects against diphtheria, pertussis, and tetanus, not tuberculosis. In summary, BCG vaccine is the correct choice as it targets tuberculosis specifically, while the other options are designed for different purposes.

Correct Answer: A

Rationale: Step-by-step rationale for why Answer A (Sabouraud's) is correct: 1. Sabouraud's agar is a selective medium for fungi. 2. Candida is a type of fungus causing candidosis. 3. Sabouraud's agar promotes fungal growth. 4. Candida will grow on Sabouraud's agar, confirming the diagnosis. 5. Other choices are for bacterial culture, not suitable for fungal growth. Summary: - Endo, Jensen's, and Roux are not appropriate for fungal culture. - Sabouraud's agar specifically supports fungal growth, making it the correct choice for confirming candidosis.

Correct Answer: A

Rationale: The correct answer is A: aspergillosis and candidiasis. Detection of galactomannan and free mannan is commonly used in diagnosing these fungal infections. Galactomannan is a component of the cell wall of Aspergillus species, while free mannan is associated with Candida species. This detection method helps in identifying these specific fungal infections accurately. B: Syphilis is caused by a bacterium, Treponema pallidum, and is not diagnosed using galactomannan or free mannan detection. C: Leptospirosis is a bacterial infection caused by the Leptospira species and is not diagnosed using galactomannan or free mannan detection. D: HIV infection is a viral infection caused by the human immunodeficiency virus and is not diagnosed using galactomannan or free mannan detection.