Which bacteria are responsible for causing bacterial meningitis?

Correct Answer: D

Rationale: The correct answer is D, "All of the above." Bacterial meningitis can be caused by Neisseria meningitidis, Haemophilus influenzae, and Streptococcus pneumoniae. These bacteria are common pathogens associated with meningitis. Each of them can lead to serious infections in the brain and spinal cord. Neisseria meningitidis is known for causing meningococcal meningitis, Haemophilus influenzae is a common cause of H. influenzae meningitis, and Streptococcus pneumoniae is responsible for pneumococcal meningitis. Therefore, since all three bacteria can cause bacterial meningitis, the correct answer is D. Choices A, B, and C are incorrect because each of these bacteria individually can cause bacterial meningitis; it is not limited to just one specific type.

Correct Answer: C

Rationale: The primary target of beta-lactam antibiotics is cell wall synthesis. These antibiotics inhibit enzymes called penicillin-binding proteins, which are essential for building the bacterial cell wall. By disrupting cell wall synthesis, beta-lactam antibiotics weaken the cell wall, leading to bacterial cell lysis and death. Protein synthesis (Choice A), DNA replication (Choice B), and folic acid synthesis (Choice D) are not directly targeted by beta-lactam antibiotics, making them incorrect choices.

Correct Answer: B

Rationale: Answer B, Infectious mononucleosis, is not caused by enteroviruses. Infectious mononucleosis is primarily caused by the Epstein-Barr virus, a member of the herpesvirus family, not by enteroviruses. Enteroviruses are known to cause diseases such as myocarditis, herpangina, and Boston exanthema. Therefore, B is the correct answer. Myocarditis, herpangina, and Boston exanthema can all be caused by enteroviruses, making choices A, C, and D incorrect, respectively.

Correct Answer: A

Rationale: The correct answer is A: Rotavirus. Rotavirus is a member of the Reoviridae family known for causing diarrhea in infants. It infects the lining of the small intestine, leading to symptoms like vomiting and watery diarrhea. Rationale: 1. Rotavirus is specifically known for causing diarrhea in infants. 2. Reoviruses are a family of viruses to which rotavirus belongs. 3. Congovirus (B), Hepadnavirus (C), and Picornavirus (D) do not belong to the Reoviridae family and are not associated with causing diarrhea in infants. In summary, choice A is correct as it aligns with the characteristics of the given family of viruses and their associated symptoms, while choices B, C, and D are incorrect as they do not fit these criteria.

Correct Answer: B

Rationale: The correct answer is B because filoviruses, such as Ebola virus, require investigation in specifically equipped laboratories with high biological protection due to their high pathogenicity and risk of transmission. This is essential for ensuring the safety of researchers and preventing outbreaks. A: This is incorrect as filoviruses are not the most common cause of gastroenteritis; they primarily cause severe hemorrhagic fevers. C: Filoviruses are not widespread; they are typically confined to specific regions during outbreaks. D: Mass immunization is not used for filoviruses as there is no established vaccine for general prophylaxis.

Correct Answer: A

Rationale: The correct answer is A: Anatoxin. An anatoxin is a preparation that contains inactivated toxins produced by the anthrax-causing bacteria. By administering anatoxin, the population can develop immunity against the toxin without being exposed to the live bacteria. This specific prophylaxis approach helps prevent the development of anthrax infection by targeting the toxin itself. Summary: - Choice B (Inactivated vaccine) is incorrect because an inactivated vaccine typically contains killed or inactivated whole bacteria, not just the toxins. - Choice C (Chemical vaccine) is incorrect as there is no such thing as a chemical vaccine; vaccines are biological preparations. - Choice D (Genetically engineered vaccine) is incorrect because while vaccines can be genetically engineered, the specific term "genetically engineered vaccine" does not accurately describe the prophylaxis used against anthrax in this scenario.

Correct Answer: C

Rationale: Rationale: Metronidazole is the drug of choice for systemic amebiasis due to its high efficacy against Entamoeba histolytica. It has good tissue penetration and can treat intestinal, liver, and lung involvement. Quiniofone (A) has limited use and is not recommended for amebiasis. Enteroseptol (B) is not effective against systemic amebiasis. Tetracycline (D) is not the first-line treatment for amebiasis and has limited efficacy against Entamoeba histolytica.

Correct Answer: B

Rationale: The correct answer is B because live vaccines can potentially revert to a virulent form, although this is extremely rare. This is due to the live attenuated virus in the vaccine potentially mutating back to a more dangerous form. Live vaccines are designed to be weakened but there is a small risk of reversion. Therefore, statement B is not correct. A: This statement is correct as immunocompromised individuals may have adverse reactions to live vaccines due to their weakened immune system. C: This statement is correct as microbes with many serotypes can make it challenging to develop a vaccine that covers all variations. D: This statement is correct as side effects to vaccination, although usually mild and temporary, can occur in some individuals.

Correct Answer: B

Rationale: The correct answer is B: pertussis toxin. This toxin is the most important virulence factor of Bordetella pertussis because it plays a key role in causing the characteristic symptoms of whooping cough. Pertussis toxin interferes with the host's immune response, leading to inflammation and tissue damage in the respiratory tract. The other choices (A: the flagellum, C: P fimbriae, D: mannose-resistant adhesins) are important for bacterial attachment and colonization, but they do not directly contribute to the severity of the disease like pertussis toxin does.